CIT

Gene Symbol CIT
Entrez Gene 11113
Alt Symbol CRIK, STK21
Species Human
Gene Type protein-coding
Description citron rho-interacting serine/threonine kinase
Other Description citron (rho-interacting, serine/threonine kinase 21)|citron Rho-interacting kinase|serine/threonine kinase 21|serine/threonine-protein kinase 21
Swissprots Q9UPZ7 O14578 Q6XUH8 Q86UQ9 Q2M5E1
Accessions AAB71327 EAW98155 EAW98156 EAW98157 EAW98158 O14578 AB023166 BAA76793 AK123136 AY209000 AAP43922 AY257469 AAP13528 AY681966 AAV87216 BC008127 BC047647 BC156529 AAI56530 BC172522 AAI72522 XM_006719206 XP_006719269 XM_011537783 XP_011536085 XM_011537784 XP_011536086 XM_011537785 XP_011536087 XM_011537786 XP_011536088 XM_011537787 XP_011536089 XM_011537788 XP_011536090 XM_011537789 XP_011536091 XM_011537790 XP_011536092 XM_011537791 XP_011536093 XM_011537792 XP_011536094 NM_001206999 NP_001193928 NM_007174 NP_009105
Function Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2. {ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:16431929, ECO:0000269|PubMed:21457715}.
Subcellular Location Cytoplasm {ECO:0000250}.

Active human CIT protein fragment - ab179954 from Abcam

Category Protein
Prices $288.00
Sizes 5 µg
Source Baculovirus infected sf9 cells
Species Human
Sample Kinase Activity Plot. The specific activity of ab179954 was determined to be 5 nmol/min/mg.

Citron Rho-interacting kinase protein - 80R-4195 from Fitzgerald

Category Protein
Prices $1,295.00
Sizes 500 µg
Source E.coli
Species Human

CRIK - H00011113-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CRIK - H00011113-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CRIK - P5530 from Acris Antibodies

Category Protein
Prices $1,010.00
Sizes 5 µg
Species Human

Recombinant Human CIT, GST-tagged - CIT-827H from Creative Biomart

Category Protein
Source Sf9 insect cells using baculovirus
Species Human

Recombinant Human Citron Rho-interacting kinase(CIT) ,partial - CSB-YP005446HU CSB-EP005446HU CSB-BP005446HU CSB-MP005446HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CIT-Antibody-C-term-Blocking-Peptide - BP7124b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CIT-Antibody-Center-Blocking-Peptide - BP7124a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Citron Rho-interacting kinase (CIT), partial, Recombinant Protein - MBS1147757 from MyBioSource

Category Protein
Prices $1,015.00, $1,015.00, $1,245.00, $1,245.00, $1,540.00, $1,540.00, $1,995.00, $1,995.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

STK21, Recombinant Protein - MBS515484 from MyBioSource

Category Protein
Prices $315.00, $425.00
Sizes 5 µg, 10 µg
Source Sf9 insect cells using baculovirus
Species Human
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