CIT

Gene Symbol CIT
Entrez Gene 11113
Alt Symbol CRIK, STK21
Species Human
Gene Type protein-coding
Description citron rho-interacting serine/threonine kinase
Other Description citron (rho-interacting, serine/threonine kinase 21)|citron Rho-interacting kinase|serine/threonine kinase 21|serine/threonine-protein kinase 21
Swissprots Q9UPZ7 O14578 Q6XUH8 Q86UQ9 Q2M5E1
Accessions AAB71327 EAW98155 EAW98156 EAW98157 EAW98158 O14578 AB023166 BAA76793 AK123136 AY209000 AAP43922 AY257469 AAP13528 AY681966 AAV87216 BC008127 BC047647 BC156529 AAI56530 BC172522 AAI72522 XM_006719206 XP_006719269 XM_011537783 XP_011536085 XM_011537784 XP_011536086 XM_011537785 XP_011536087 XM_011537786 XP_011536088 XM_011537787 XP_011536089 XM_011537788 XP_011536090 XM_011537789 XP_011536091 XM_011537790 XP_011536092 XM_011537791 XP_011536093 XM_011537792 XP_011536094 NM_001206999 NP_001193928 NM_007174 NP_009105
Function Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2. {ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:16431929, ECO:0000269|PubMed:21457715}.
Subcellular Location Cytoplasm {ECO:0000250}.

CRIK (A-6) - sc-398095 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CRIK (A-6): sc-398095. Western blot analysis of CRIK expression in non-transfected 293T: sc-117752 (A), human CRIK transfected 293T: sc-372308 (B), Jurkat (C), HeLa (D) and BJAB (E) whole cell lysates.

CRIK (C-5) - sc-377449 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CRIK (C-5): sc-377449. Western blot analysis of CRIK expression in BJAB (A) and Jurkat (B) whole cell lysates.

CRIK (E-6) - sc-390437 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CRIK (E-6): sc-390437. Western blot analysis of CRIK expression in Jurkat (A), BJAB (B) and HeLa (C) whole cell lysates.

CRIK (C-20) - sc-1848 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CRIK (C-20):sc-1848. Western blot analysis of CRIK expression in HeLa (A), Jurkat (B) and BJAB (C) whole cell lysates.

CRIK (E-14) - sc-11630 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CRIK (H-300) - sc-366163 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CRIK (H-300): sc-366163. Western blot analysis of CRIK expression in non-transfected 293T: sc-117752 (A), human CRIK transfected 293T: sc-372308 (B) and Ramos (C) whole cell lysates.

CRIK (G-14) - sc-11627 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CRIK (S-20) - sc-1949 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CRIK (S-20):sc-1949. Western blot analysis of CRIK expression in BJAB whole cell lysate.

CRIK (6) - sc-136283 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
CRIK (6): sc-136283. Western blot analysis of CRIK expression in PC-12 whole cell lysate.

Anti-CIT antibody - ab86782 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CIT antibody (ab86782) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-CIT antibody - ab110897 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab110897, at a 1/50 dilution, staining CIT in paraffin-embedded Human brain tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-CIT / CRIK / Citron Antibody (aa1011-1060) - LS-C118658 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (C-Terminus, AP) - LS-C218782 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (C-Terminus, FITC) - LS-C218784 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (C-Terminus, APC) - LS-C218783 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (C-Terminus, Azide-free, HRP) - LS-C218786 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (C-Terminus, Biotin) - LS-C218785 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (Internal, AP) - LS-C218787 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (Internal, APC) - LS-C218788 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (C-Terminus, PE) - LS-C218789 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (Internal, Biotin) - LS-C218790 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (Internal, FITC) - LS-C218791 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (Internal, Azide-free, HRP) - LS-C218793 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (Internal, PE) - LS-C218792 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIT / CRIK / Citron Antibody (Internal) - LS-C327075 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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