PSMC3IP

Gene Symbol PSMC3IP
Entrez Gene 29893
Alt Symbol GT198, HOP2, HUMGT198A, ODG3, TBPIP
Species Human
Gene Type protein-coding
Description PSMC3 interacting protein
Other Description DBD-interacting|TBP-1-interacting protein|homologous-pairing protein 2 homolog|nuclear receptor coactivator GT198|proteasome 26S ATPase subunit 3-interacting protein|tat-binding protein 1-interacting protein
Swissprots Q8WXG2 Q14458 C5ILB7 Q9P2W1 Q96HA2
Accessions EAW60846 EAW60847 EAW60848 EAW60849 EAW60850 Q9P2W1 AB030304 BAA92872 AF440240 AAL33609 AK126369 BC008792 AAH08792 BI115923 DB494067 FJ952179 ACR46654 FJ952180 ACR46655 FJ952181 ACR46656 FJ952182 ACR46657 FJ952183 ACR46658 GQ851964 ACX30903 GQ851965 ACX30904 U18921 NM_001256014 NP_001242943 NM_001256015 NP_001242944 NM_001256016 NP_001242945 NM_013290 NP_037422 NM_016556 NP_057640 NR_045669 NR_045670 NR_045671
Function Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1- promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Acts as a tissue specific coactivator of hormone-dependent transcription mediated by nuclear receptors. {ECO:0000269|PubMed:10806355, ECO:0000269|PubMed:16407260, ECO:0000269|PubMed:21963259}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11739747}.
Tissue Specificity Highly expressed in testis and colon. {ECO:0000269|PubMed:11739747, ECO:0000269|PubMed:7490091}.

TBPIP (C-14) - sc-162288 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TBPIP (A-5) - sc-514014 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TBPIP (A-5): sc-514014. Western blot analysis of TBPIP expression in Hep G2 (A), Jurkat (B), K-562 (C) and U-251-MG (D) whole cell lysates.

TBPIP (D-12) - sc-162289 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TBPIP (T-21) - sc-134056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
TBPIP (T-21): sc-134056. Western blot analysis of TBPIP expression in Jurkat (A), K-562 (B) and U-698-M (C) whole cell lysates and HeLa nuclear extract (D).

Anti-PSMC3IP antibody - ab82772 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PSMC3IP antibody (ab82772) at 1 µg/ml + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PSMC3IP antibody - ab68786 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-PSMC3IP antibody (ab68786) at 1/500 dilutionLane 1 : PSMC3IP transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/5000 dilutiondeveloped using the ECL technique

Anti-PSMC3IP Antibody (aa143-192) - LS-C81089 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.

Anti-PSMC3IP Antibody (C-Terminus) - LS-C81090 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

PSMC3IP Antibody - NBP1-92301 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PSMC3IP Antibody [NBP1-92301] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

PSMC3IP Antibody - NBP1-79238 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PSMC3IP Antibody [NBP1-79238] - 721_B cell lysate, concentration 0.2-1 ug/ml.

PSMC3IP Antibody - NBP1-79237 from Novus Biologicals

Prices $139.00, $299.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PSMC3IP Antibody [NBP1-79237] - Titration: 1.25ug/ml Positive Control: HepG2 cell lysate.

PSMC3IP Antibody - H00029893-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PSMC3IP Antibody [H00029893-B01] - analysis of TBPIP expression in transfected 293T cell line by TBPIP MaxPab polyclonal antibody (B01). Lane 1: TBPIP transfected lysate (24.90 KDa). Lane 2: Non-transfected lysate.

PSMC3IP Antibody - H00029893-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PSMC3IP Antibody [H00029893-B01P] - Analysis of PSMC3IP expression in transfected 293T cell line by PSMC3IP polyclonal antibody. Lane 1: TBPIP transfected lysate(23.87 KDa). Lane 2: Non-transfected lysate.

Anti-PSMC3IP antibody produced in rabbit - HPA044439 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PSMC3IP: <B>Cat. No. HPA044439</B>: Immunohistochemical staining of human testis shows moderate nuclear positivity in cells in seminiferus ducts.

Anti-PSMC3IP antibody produced in mouse - SAB1407389 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PSMC3IP: <B>Cat. No. SAB1407389</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~23.9 kDa using PSMC3IP transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PSMC3IP antibody produced in rabbit - AV47613 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV47613</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2

PSMC3IP antibody - middle region (ARP47613_T100) - ARP47613_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PSMC3IP antibody - C-terminal region (ARP47615_P050) - ARP47615_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PSMC3IP antibody - 70R-8725 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PSMC3IP antibody - 70R-19593 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

PSMC3IP antibody - 20R-1263 from Fitzgerald

Prices $290.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PSMC3IP antibody - 11339-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
K562 cell were subjected to SDS PAGE followed by western blot with 11339-1-AP(PSMC3IP Antibody) at dilution of 1:800

PSMC3IP antibody - H00029893-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of PSMC3IP expression in transfected 293T cell line (H00029893-T01) by PSMC3IP MaxPab polyclonal antibody.Lane 1: TBPIP

PSMC3IP antibody - H00029893-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

PSMC3IP Antibody - 26-245 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human 721_B cells at 0.2-1 ug/ml.
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