Gene Symbol | MEIS1 |
---|---|
Entrez Gene | 4211 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | Meis homeobox 1 |
Other Description | Meis1, myeloid ecotropic viral integration site 1 homolog|WUGSC:H_NH0444B04.1|homeobox protein Meis1|leukemogenic homolog protein |
Swissprots | A8MV50 O00470 |
Accessions | AAN40012 AAY15006 AAY24268 BAB15814 EAW99892 EAW99893 EAW99894 EAW99895 EAW99896 O00470 AI203963 AK098174 BAG53586 AK297109 BAH12499 AK297817 BAH12671 AK314949 BAG37454 AL832770 BC036511 BC043503 AAH43503 CB854199 U85707 AAC51642 XM_005264321 XP_005264378 XM_005264322 XP_005264379 XM_005264323 XP_005264380 XM_005264324 XP_005264381 XM_005264325 XP_005264382 XR_244932 XR_244933 NM_002398 NP_002389 |
Function | Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. {ECO:0000269|PubMed:12609849}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
Tissue Specificity | Expressed at low level in normal immunohepatopoietic tissues, including the fetal liver. Expressed in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. Also expressed at high levels in the cerebellum. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer |
Human MEIS1 full length protein - ab112320 from Abcam
|
||||||||||
Human MEIS1 peptide - ab22467 from Abcam
|
||||||||||
Human MEIS1 protein fragment - ab112321 from Abcam
|
||||||||||
MEIS1 Antibody Blocking Peptide - LS-E11188 from LifeSpan Bioscience
|
||||||||||
MEIS1 Antibody Blocking Peptide - LS-E13696 from LifeSpan Bioscience
|
||||||||||
MEIS1 Antibody Blocking Peptide - LS-E13697 from LifeSpan Bioscience
|
||||||||||
MEIS1 Antibody Blocking Peptide - LS-E26926 from LifeSpan Bioscience
|
||||||||||
Recombinant Human MEIS1 Protein - H00004211-P01 from Novus Biologicals
|
||||||||||
Recombinant Human MEIS1 Protein - H00004211-Q01 from Novus Biologicals
|
||||||||||
MEIS1 blocking peptide - GTX88513-PEP from GeneTex
|
||||||||||
MEIS1 Peptide - AC21-1757-P from Abcore
|
||||||||||
MEIS1 - H00004211-P01-10 from Acris Antibodies
|
||||||||||
MEIS1 - H00004211-P01-25 from Acris Antibodies
|
||||||||||
MEIS1 - H00004211-Q01-10 from Acris Antibodies
|
||||||||||
MEIS1 - H00004211-Q01-25 from Acris Antibodies
|
||||||||||
MEIS1 Peptide - 46-767P from ProSci
|
||||||||||
MEIS1 fusion protein - ag13559 from Proteintech Group
|
||||||||||
Recombinant Human MEIS1 - MEIS1-26868TH from Creative Biomart
|
||||||||||
Recombinant Human MEIS1 - MEIS1-29559TH from Creative Biomart
|
||||||||||
Meis1 (I278) Peptide - BS3488P from Bioworld Technology
|
||||||||||
Recombinant Human Homeobox protein Meis1(MEIS1) - CSB-YP013686HU CSB-EP013686HU CSB-BP013686HU CSB-MP013686HU from Cusabio
|
||||||||||
MEIS1 , Peptide - MBS425732 from MyBioSource
|
||||||||||
MEIS1 Recombinant Protein Antigen - NBP2-38776PEP from Novus Biologicals
|
||||||||||
MEIS1 Blocking Peptide - abx161945 from Abbexa
|
||||||||||
MEIS1 Peptide, Human - M34GP09398H from Creative Peptides
|