MEIS1

Gene Symbol MEIS1
Entrez Gene 4211
Alt Symbol -
Species Human
Gene Type protein-coding
Description Meis homeobox 1
Other Description Meis1, myeloid ecotropic viral integration site 1 homolog|WUGSC:H_NH0444B04.1|homeobox protein Meis1|leukemogenic homolog protein
Swissprots A8MV50 O00470
Accessions AAN40012 AAY15006 AAY24268 BAB15814 EAW99892 EAW99893 EAW99894 EAW99895 EAW99896 O00470 AI203963 AK098174 BAG53586 AK297109 BAH12499 AK297817 BAH12671 AK314949 BAG37454 AL832770 BC036511 BC043503 AAH43503 CB854199 U85707 AAC51642 XM_005264321 XP_005264378 XM_005264322 XP_005264379 XM_005264323 XP_005264380 XM_005264324 XP_005264381 XM_005264325 XP_005264382 XR_244932 XR_244933 NM_002398 NP_002389
Function Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. {ECO:0000269|PubMed:12609849}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Tissue Specificity Expressed at low level in normal immunohepatopoietic tissues, including the fetal liver. Expressed in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. Also expressed at high levels in the cerebellum.
Top Pathways Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

Meis1 CRISPR/Cas9 KO Plasmid (h) - sc-401481 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 HDR Plasmid (h) - sc-401481-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 Double Nickase Plasmid (h) - sc-401481-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 Double Nickase Plasmid (h2) - sc-401481-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 CRISPR Activation Plasmid (h) - sc-401481-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 CRISPR Activation Plasmid (h2) - sc-401481-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 Lentiviral Activation Particles (h) - sc-401481-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 Lentiviral Activation Particles (h2) - sc-401481-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 siRNA (h) - sc-35896 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Meis1 shRNA Plasmid (h) - sc-35896-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Meis1 shRNA (h) Lentiviral Particles - sc-35896-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Meis1/2 siRNA (h) - sc-43922 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Meis1/2 shRNA Plasmid (h) - sc-43922-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Meis1/2 shRNA (h) Lentiviral Particles - sc-43922-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MEIS1 RNAi - H00004211-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU119561 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13198 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13198 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09747 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09747

MEIS1 siRNA (Human) - CRH2863 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Meis1 CRISPR/Cas9 KO Plasmid (h2) - sc-401481-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Meis1 HDR Plasmid (h2) - sc-401481-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human MEIS1 (NM_002398.2) - SHH340331 from Creative biogene

Category siRNA
Species Reactivities Human

MEIS1 shRNA Plasmid (Human) - CHH2863 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MEIS1 miRNA 3'UTR clone - MiUTR1H-06203 from Creative biogene

Species Reactivities Human
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