MEIS1

Gene Symbol MEIS1
Entrez Gene 4211
Alt Symbol -
Species Human
Gene Type protein-coding
Description Meis homeobox 1
Other Description Meis1, myeloid ecotropic viral integration site 1 homolog|WUGSC:H_NH0444B04.1|homeobox protein Meis1|leukemogenic homolog protein
Swissprots A8MV50 O00470
Accessions AAN40012 AAY15006 AAY24268 BAB15814 EAW99892 EAW99893 EAW99894 EAW99895 EAW99896 O00470 AI203963 AK098174 BAG53586 AK297109 BAH12499 AK297817 BAH12671 AK314949 BAG37454 AL832770 BC036511 BC043503 AAH43503 CB854199 U85707 AAC51642 XM_005264321 XP_005264378 XM_005264322 XP_005264379 XM_005264323 XP_005264380 XM_005264324 XP_005264381 XM_005264325 XP_005264382 XR_244932 XR_244933 NM_002398 NP_002389
Function Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. {ECO:0000269|PubMed:12609849}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Tissue Specificity Expressed at low level in normal immunohepatopoietic tissues, including the fetal liver. Expressed in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. Also expressed at high levels in the cerebellum.
Top Pathways Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

MEIS1/2 Antibody - 12744 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293 cells, mock transfected (-) or transfected with constructs expressing Myc/DDK-tagged full-length human MEIS1 (hMEIS1-Myc/DDK; +) or MEIS2 (hMEIS2-Myc/DDK; +), using MEIS1/2 Antibody.

Meis1/2 (C-17) - sc-10599 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Meis1/2 (C-17): sc-10599. Western blot analysis of Meis1/2 expression in MCP-5 (A), MEG-01 (B), CCRF-CEM (C) and IMR-32 (D) whole cell lysates.

Meis1/2 (N-17) - sc-10596 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Meis1/2 (N-17): sc-10596. Western blot analysis of Meis2 expression in non-transfected: sc-117752 (A) and human Meis2 transfected: sc-116143 (B) 293T whole cell lysates.

Meis1/2/3 (9.2.7) - sc-101850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Meis1/2/3 (9.2.7): sc-101850. Western blot analysis of Meis2 expression in non-transfected: sc-117752 (A) and human Meis2 transfected: sc-116143 (B) 293T whole cell lysates.

Meis1/2 (H-80) - sc-25412 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Meis1/2 (H-80): sc-25412. Western blot analysis of Meis1/2 expression in CCRF-CEM (A), HeLa (B), HL-60 (C), K-562 (D) and M1 (E) whole cell lysates.

Anti-MEIS1 antibody - ab167510 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-MEIS1 antibody (ab167510) at 1 µg/mlLane 1 : MEIS1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Mouse IgG HRP at 1/2500 dilution

Anti-MEIS1 antibody [EPR5781] - ab124686 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5781
All lanes : Anti-MEIS1 antibody [EPR5781] (ab124686) at 1/10000 dilutionLane 1 : U-87 MG cell lysateLane 2 : K562 cell lysateLane 3 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-MEIS1 antibody - ChIP Grade - ab19867 from Abcam

Prices $400.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MEIS1 antibody - ChIP Grade (ab19867) at 1 µg/ml (blocked with 5% milk) + KG-1 (Human myeloid cell line) Nuclear Lysate at 15 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutionPerformed under reducing conditions.

Anti-MEIS1 Antibody (Ile278) - LS-C177551 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MEIS1 Antibody - LS-C311377 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MEIS1 Antibody (aa136-377) - LS-C311604 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MEIS1 Antibody (aa24-73) - LS-C145858 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MEIS1 antibody LS-C145858 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.

Anti-MEIS1 Antibody (aa179-228) - LS-C109633 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MEIS1 antibody LS-C109633 Western blot of Fetal Lung lysate.

Anti-MEIS1 Antibody (C-Terminus) - LS-C80180 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal liver lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-MEIS1 Antibody (aa280-330) IHC-plus™ - LS-B7807 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MEIS1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7807 dilution 10 ug/ml.

Anti-MEIS1 Antibody (Internal, clone EPR5781) - LS-C138787 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5781
Western blot analysis on (A) U87-MG, (B) K562, and (C) HeLa cell lysates using anti-MEIS1 antibody.

Anti-MEIS1 Antibody (aa170-220) - LS-C148605 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of MEIS1 in mouse embryo brain lysate in the 1) absence and 2) presence of immunizing peptide using LS-C148605 at3 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

Anti-MEIS1 Antibody (aa198-210) - LS-C87380 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.1 ug/ml) staining of Human Cerebral Cortex lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

Anti-MEIS1 Antibody (aa229-278) IHC-plus™ - LS-B11422 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MEIS1 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11422 concentration 20 ug/ml.

Anti-MEIS1/MEIS2/MEIS3 Antibody (aa60-390) - LS-C72347 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

MEIS1 Antibody - NBP2-24597 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MEIS1 Antibody [NBP2-24597] - Analysis of MEIS1 in mouse embryo brain lysate in the 1) absence and 2) presence of immunizing peptide using NBP2-24597 at 3 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

MEIS1 Antibody - NBP2-24522 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: MEIS1 Antibody [NBP2-24522] - Analysis of MEIS1 in formalin-fixed, paraffin-embedded mouse testis tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

MEIS1 Antibody (EPR5781) - NBP1-95898 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5781
Western Blot: MEIS1 Antibody (EPR5781) [NBP1-95898] (A) U87-MG, (B) K562, and © HeLa cell lysates.

MEIS1 Antibody - NBP2-38776 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MEIS1 Antibody - NBP1-06991 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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