APLF

Gene Symbol APLF
Entrez Gene 200558
Alt Symbol APFL, C2orf13, PALF, Xip1, ZCCHH1
Species Human
Gene Type protein-coding
Description aprataxin and PNKP like factor
Other Description PNK and APTX-like FHA domain-containing protein|PNK and APTX-like FHA protein|XRCC1-interacting protein 1|aprataxin and PNK-like factor|aprataxin- and PNK-like factor|apurinic-apyrimidinic endonuclease APLF|zinc finger, CX5CX6HX5H motif containing 1
Swissprots Q53P47 Q53PB9 A8K476 Q8IW19 Q53QU0
Accessions AAY14945 AAY24008 AAY24113 EAW99871 EAW99872 Q8IW19 AK290841 BAF83530 AK308186 BC030711 BC041144 AAH41144 DA641644 NM_173545 NP_775816
Function Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic- apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. {ECO:0000269|PubMed:17353262, ECO:0000269|PubMed:17396150}.
Subcellular Location Nucleus. Cytoplasm, cytosol. Note=Localizes to DNA damage sites. Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers.

Apaxin and PNK-like factor (APLF), Human, ELISA Kit - E01A1591 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7244034 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7244041 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7215194 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7250567 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7227799 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7239628 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7244763 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7230444 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Apaxin and PNK-like factor (APLF), ELISA Kit - MBS7202294 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human APLF ELISA Kit - E075470 from Biobool

Category ELISA Kit
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