NFKBIA

Gene Symbol	NFKBIA
Entrez Gene	4792
Alt Symbol	IKBA, MAD-3, NFKBI
Species	Human
Gene Type	protein-coding
Description	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Other Description	I-kappa-B-alpha|IkappaBalpha|NF-kappa-B inhibitor alpha|ikB-alpha|major histocompatibility complex enhancer-binding protein MAD3|nuclear factor of kappa light chain gene enhancer in B-cells
Swissprots	B2R8L6 P25963
Accessions	AAD14949 AAR29599 CAB65110 CAB65111 CAB65112 CAB65113 CAB65114 CAB65556 CAM91165 CBX47574 EAW65875 P25963 AK311515 AK313421 BAG36213 AY033600 AAK51149 BC002601 AAH02601 BC004983 AAH04983 BT007091 AAP35754 BU737609 M69043 AAA16489 NM_020529 NP_065390
Function	Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. {ECO:0000269|PubMed:7479976}.
Subcellular Location	Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. {ECO:0000250}.
Top Pathways	Legionellosis, Herpes simplex infection, Viral carcinogenesis, Influenza A, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human IKB alpha (phospho Y305) peptide - ab42717 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Active human IKB alpha (phospho Y42) peptide - ab42716 from Abcam Category Peptide Prices $290.00 Sizes 50 µg Species Human

Human IKB alpha full length protein - ab113133 from Abcam Category Protein Source E. coli Species Human

Human IKB alpha full length protein - ab59981 from Abcam Category Protein Source E. coli Species Human

Human IKB alpha peptide - ab105485 from Abcam Category Peptide Species Human

Human IKB alpha protein fragment - ab61427 from Abcam Category Protein Source E. coli Species Human

IKB alpha peptide - ab7546 from Abcam Category Peptide

NFKBIA / IKB Alpha / IKBA Antibody Blocking Peptide - LS-E10552 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIA / IKB Alpha / IKBA Antibody Blocking Peptide - LS-E10580 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIA / IKB Alpha / IKBA Antibody Blocking Peptide - LS-E10637 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIA / IKB Alpha / IKBA Antibody Blocking Peptide - LS-E10924 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIA / IKB Alpha / IKBA Antibody Blocking Peptide - LS-E7466 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIA / IKB Alpha / IKBA Antibody Blocking Peptide - LS-E9406 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIA / IKB Alpha / IKBA Antibody Blocking Peptide - LS-E6971 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IkB-alpha Protein - H00004792-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IkB-alpha Peptide - NB600-640PEP from Novus Biologicals Category Peptide Prices $199.00 Sizes 50 µl

Recombinant Human IkB-alpha Protein - NBP1-72500 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

IKB-alpha-IKBA-Antibody-Blocking-peptide - BP2506a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-NFKBIASer32-Antibody-Blocking-peptide - BP3714a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

NFKBIA-Antibody--S3236--Blocking-Peptide - BP7981b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NFKBIA-Antibody-Y181-Blocking-Peptide - BP7981a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IKB alpha peptide - GTX27546 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

Human NFKBIA protein - orb168922 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

Human NFKBIA His tag protein - orb83970 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source E. coli Species Human

NFKBIA peptide - orb217667 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Sheep

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