NFKBIA

Gene Symbol	NFKBIA
Entrez Gene	4792
Alt Symbol	IKBA, MAD-3, NFKBI
Species	Human
Gene Type	protein-coding
Description	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Other Description	I-kappa-B-alpha|IkappaBalpha|NF-kappa-B inhibitor alpha|ikB-alpha|major histocompatibility complex enhancer-binding protein MAD3|nuclear factor of kappa light chain gene enhancer in B-cells
Swissprots	B2R8L6 P25963
Accessions	AAD14949 AAR29599 CAB65110 CAB65111 CAB65112 CAB65113 CAB65114 CAB65556 CAM91165 CBX47574 EAW65875 P25963 AK311515 AK313421 BAG36213 AY033600 AAK51149 BC002601 AAH02601 BC004983 AAH04983 BT007091 AAP35754 BU737609 M69043 AAA16489 NM_020529 NP_065390
Function	Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. {ECO:0000269|PubMed:7479976}.
Subcellular Location	Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. {ECO:0000250}.
Top Pathways	Legionellosis, Herpes simplex infection, Viral carcinogenesis, Influenza A, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NFKBIA gene - orb92799 from Biorbyt Prices $306.00 Sizes 10 μg Species Human

Human-NFKBIA-cDNA-Clone - DC01578 from Abgent, a WuXi AppTec company Prices $427.95 Sizes 10 µg Species Human Accession BC002601

NFKBIA - MBS1270069 from MyBioSource Species Human Accession BC004983

NFKBIA - MBS1274487 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC002601

Human IkB alpha/NFKBIA Gene ORF cDNA clone in cloning vector - HG12045-G from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, N-HA tag - HG12045-NY from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12045-ACR from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG12045-ANR from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, N-His tag - HG12045-NH from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12045-NF from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12045-NM from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12045-CF from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, C-His tag - HG12045-CH from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12045-CM from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12045-ACG from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, C-HA tag - HG12045-CY from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid - HG12045-UT from Sino Biological Species Human

Human IkB alpha/NFKBIA Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG12045-ANG from Sino Biological Species Human

Human NFKBIA ORF Clone (BC002601) - CDCS415103 from Creative biogene Species Human Accession P25963

Human NFKBIA ORF Clone (BC004983) - CDCS415104 from Creative biogene Species Human Accession P25963

Human NFKBIA ORF clone (NM_020529) - CDCB160287 from Creative biogene Species Human

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