Gene Symbol | HSF1 |
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Entrez Gene | 3297 |
Alt Symbol | HSTF1 |
Species | Human |
Gene Type | protein-coding |
Description | heat shock transcription factor 1 |
Other Description | HSF 1|HSTF 1|heat shock factor protein 1 |
Swissprots | A8MW26 A8K4L0 Q53XT4 Q00613 |
Accessions | CAM91162 EAW82131 Q00613 AF299094 AAG23698 AK054762 BAG51421 AK125467 BAG54202 AK126580 AK222497 BAD96217 AK290975 BAF83664 AK300205 BAG61976 BC014638 AAH14638 BT007351 AAP36015 DA481620 DQ893859 ABM84785 M64673 AAA52695 XM_005272315 XP_005272372 XM_005272316 XP_005272373 XM_005272317 XP_005272374 XM_011517004 XP_011515306 XM_011517005 XP_011515307 XM_011517006 XP_011515308 XR_246618 NM_005526 NP_005517 |
Function | DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. {ECO:0000269|PubMed:11447121, ECO:0000269|PubMed:11583998, ECO:0000269|PubMed:12659875, ECO:0000269|PubMed:12665592, ECO:0000269|PubMed:16278218, ECO:0000269|PubMed:8946918, ECO:0000269|PubMed:9121459, ECO:0000269|PubMed:9535852}. |
Subcellular Location | Cytoplasm. Nucleus. Note=Cytoplasmic during normal growth. On activation, translocates to nuclear stress granules. Colocalizes with SUMO1 in nuclear stress granules. |
Top Pathways | Legionellosis |
HSF1 full length protein - ab115715 from Abcam
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Human HSF1 (phospho ) full length protein - ab115508 from Abcam
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Human HSF1 full length protein - ab78795 from Abcam
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Human HSF1 full length protein - ab116422 from Abcam
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HSF1 Antibody Blocking Peptide - LS-E3053 from LifeSpan Bioscience
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HSF1 Antibody Blocking Peptide - LS-E10826 from LifeSpan Bioscience
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HSF1 Antibody Blocking Peptide - LS-E13229 from LifeSpan Bioscience
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HSF1 Antibody Blocking Peptide - LS-E13230 from LifeSpan Bioscience
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HSF1 Antibody Blocking Peptide - LS-E6969 from LifeSpan Bioscience
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HSF1 Protein - NBC1-18373 from Novus Biologicals
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HSF1 Partial Recombinant Protein - H00003297-Q01 from Novus Biologicals
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HSF1 Recombinant Protein - H00003297-P01 from Novus Biologicals
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HSF1-Antibody-N-term-Blocking-Peptide - BP14189a from Abgent, a WuXi AppTec company
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HSF1-Sumoylation-site-Antibody-Blocking-Peptide - BP2501a from Abgent, a WuXi AppTec company
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HSF1 Protein (OPPA01698) - OPPA01698 from Aviva Systems Biology
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Human Heat Shock Transcription Factor-1 protein - orb81501 from Biorbyt
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HSF1 Blocking Peptide - 33R-10927 from Fitzgerald
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HSF1 Blocking Peptide - 33R-1587 from Fitzgerald
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HSF1 Blocking Peptide - 33R-10256 from Fitzgerald
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HSF1 protein (His tag) - 80R-1054 from Fitzgerald
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Human HSF1 Protein - abx067025 from Abbexa
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Heat shock factor 1 / HSF1 - AR03000PU-N from Acris Antibodies
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Heat shock factor 1 / HSF1 - AR03000PU-S from Acris Antibodies
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Heat shock factor 1 / HSF1 - H00003297-P01-10 from Acris Antibodies
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Heat shock factor 1 / HSF1 - H00003297-P01-25 from Acris Antibodies
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