Gene Symbol | CERS4 |
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Entrez Gene | 79603 |
Alt Symbol | LASS4, Trh1 |
Species | Human |
Gene Type | protein-coding |
Description | ceramide synthase 4 |
Other Description | LAG1 homolog, ceramide synthase 4|LAG1 longevity assurance homolog 4 |
Swissprots | D6W665 Q9HA82 |
Accessions | EAW68940 EAW68941 EAW68942 EAW68943 EAW68944 EAW68945 Q9HA82 AK022151 BAB13972 AK055414 AK222621 BAD96341 AK225394 BC009828 AAH09828 BC063621 DA381485 DQ893215 ABM84141 DQ896544 ABM87543 XM_006722896 XP_006722959 XM_006722898 XP_006722961 XM_011528288 XP_011526590 XM_011528289 XP_011526591 XM_011528290 XP_011526592 XM_011528291 XP_011526593 XM_011528292 XP_011526594 XM_011528293 XP_011526595 XM_011528294 XP_011526596 XM_011528295 XP_011526597 XM_011528296 XP_011526598 NM_024552 NP_078828 |
Function | May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Sphingolipid signaling pathway, Sphingolipid metabolism |
Human LASS4 full length protein - ab164045 from Abcam
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Human LASS4 protein fragment - ab164046 from Abcam
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LASS4 Antibody Blocking Peptide - LS-E14335 from LifeSpan Bioscience
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LASS4 Antibody Blocking Peptide - LS-E12852 from LifeSpan Bioscience
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LASS4 Antibody Blocking Peptide - LS-E13387 from LifeSpan Bioscience
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Recombinant Human LASS4 Protein - H00079603-P01 from Novus Biologicals
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Recombinant Human LASS4 Protein - H00079603-Q01 from Novus Biologicals
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Lass4 peptide - orb108432 from Biorbyt
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LASS4 Blocking Peptide - abx063975 from Abbexa
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LASS4 - H00079603-P01-10 from Acris Antibodies
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LASS4 - H00079603-P01-25 from Acris Antibodies
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LASS4 - H00079603-Q01-10 from Acris Antibodies
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LASS4 - H00079603-Q01-25 from Acris Antibodies
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LASS4 Control Peptide - AP05281CP-N from Acris Antibodies
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LASS4 fusion protein - ag14452 from Proteintech Group
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LASS4 fusion protein - Ag14133 from Proteintech Group
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Recombinant Human CERS4 - CERS4-1401H from Creative Biomart
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LASS4 Blocking Peptide - CBP2781 from Cohesion Biosciences
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CERS4 Peptide (OEEG01149) - OEEG01149 from Aviva Systems Biology
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LASS4 - TP303402 from Acris Antibodies
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Lass4, Peptide - MBS396436 from MyBioSource
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LASS4 Protein - NBP2-38735PEP from Novus Biologicals
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CERS4-Blocking-Peptide-N-Term - BP21979a from Abgent, a WuXi AppTec company
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CERS4 Peptide, Human - M34GP03016H from Creative Peptides
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Ceramide synthase 4 (CERS4), Recombinant Protein - MBS7011390 from MyBioSource
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