CERS4

Gene Symbol CERS4
Entrez Gene 79603
Alt Symbol LASS4, Trh1
Species Human
Gene Type protein-coding
Description ceramide synthase 4
Other Description LAG1 homolog, ceramide synthase 4|LAG1 longevity assurance homolog 4
Swissprots D6W665 Q9HA82
Accessions EAW68940 EAW68941 EAW68942 EAW68943 EAW68944 EAW68945 Q9HA82 AK022151 BAB13972 AK055414 AK222621 BAD96341 AK225394 BC009828 AAH09828 BC063621 DA381485 DQ893215 ABM84141 DQ896544 ABM87543 XM_006722896 XP_006722959 XM_006722898 XP_006722961 XM_011528288 XP_011526590 XM_011528289 XP_011526591 XM_011528290 XP_011526592 XM_011528291 XP_011526593 XM_011528292 XP_011526594 XM_011528293 XP_011526595 XM_011528294 XP_011526596 XM_011528295 XP_011526597 XM_011528296 XP_011526598 NM_024552 NP_078828
Function May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity). {ECO:0000250}.
Subcellular Location Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

Human LASS4 full length protein - ab164045 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164045 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human LASS4 protein fragment - ab164046 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164046 on a 12.5% SDS-PAGE stained with Coomassie Blue.

LASS4 Antibody Blocking Peptide - LS-E14335 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

LASS4 Antibody Blocking Peptide - LS-E12852 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

LASS4 Antibody Blocking Peptide - LS-E13387 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human LASS4 Protein - H00079603-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human LASS4 Protein - H00079603-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Lass4 peptide - orb108432 from Biorbyt

Category Peptide
Prices $374.00
Sizes 50 μg
Species Human

LASS4 Blocking Peptide - abx063975 from Abbexa

Category Peptide
Species Human, Monkey

LASS4 - H00079603-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

LASS4 - H00079603-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

LASS4 - H00079603-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

LASS4 - H00079603-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

LASS4 Control Peptide - AP05281CP-N from Acris Antibodies

Category Peptide
Prices $205.00
Sizes 50 µg
Western blot analysis using LAG1 longevity assurance homolog 4 at 0.75µg/ml on human lung lysate14 ug/lane. Lane A] conjugate alone, Lane B] antibody plus 27 µg blocking peptide, Lane C] antibody alone. Visualized using Pierce West Femto substrate system. Anti Rabbit secondary used at 1:3.5K dilution. Exposure for 5 minutes.

LASS4 fusion protein - ag14452 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

LASS4 fusion protein - Ag14133 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human CERS4 - CERS4-1401H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

LASS4 Blocking Peptide - CBP2781 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Monkey

CERS4 Peptide (OEEG01149) - OEEG01149 from Aviva Systems Biology

Category Peptide
Prices $150.00
Sizes 50 µg
Species Human

LASS4 - TP303402 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
LASS4

Lass4, Peptide - MBS396436 from MyBioSource

Category Peptide
Prices $195.00
Sizes 50 µg
Species Human

LASS4 Protein - NBP2-38735PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

CERS4-Blocking-Peptide-N-Term - BP21979a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CERS4 Peptide, Human - M34GP03016H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Ceramide synthase 4 (CERS4), Recombinant Protein - MBS7011390 from MyBioSource

Category Protein
Prices $1,200.00, $2,185.00, $3,395.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human
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