NDC80

Gene Symbol	NDC80
Entrez Gene	10403
Alt Symbol	HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80
Species	Human
Gene Type	protein-coding
Description	NDC80 kinetochore complex component
Other Description	NDC80 homolog, kinetochore complex component|NDC80 kinetochore complex component homolog|highly expressed in cancer protein|highly expressed in cancer, rich in leucine heptad repeats|kinetochore associated 2|kinetochore protein Hec1|kinetochore protein NDC80 homolog|kinetochore-associated protein 2|retinoblastoma-associated protein HEC
Swissprots	Q6PJX2 O14777
Accessions	CAM84948 CCQ77692 CCQ77701 CCQ77710 CCQ77719 CDH48198 CDH61620 CDH61674 CDH61693 CDH88991 CDH92529 CDH92543 CDH92554 CDH92801 CDH92898 CDI44673 CDI44682 EAX01696 EAX01697 O14777 AF017790 AAB80726 AK289396 BAF82085 AK313184 BAG36001 BC005239 AAH05239 BC010171 BC035617 AAH35617 DQ890765 ABM81691 DQ893928 ABM84854 NM_006101 NP_006092
Function	Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. {ECO:0000269|PubMed:12351790, ECO:0000269|PubMed:14654001, ECO:0000269|PubMed:14699129, ECO:0000269|PubMed:15062103, ECO:0000269|PubMed:15235793, ECO:0000269|PubMed:15239953, ECO:0000269|PubMed:15548592, ECO:0000269|PubMed:16732327, ECO:0000269|PubMed:9315664}.
Subcellular Location	Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HEC1 full length protein - ab131907 from Abcam Category Protein Source Wheat germ Species Human

Human HEC1 peptide - ab35706 from Abcam Category Peptide

Human HEC1 peptide - ab22944 from Abcam Category Peptide Species Human

HEC1 / NDC80 Antibody Blocking Peptide - LS-E25420 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NDC80 Protein - H00010403-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NDC80 Protein - H00010403-Q01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Hec1 (non-phospho Ser 165) blocking peptide - GTX70012-PEP from GeneTex Category Peptide Prices $199.00 Sizes 100 μg Species Human, Mouse, Rat

Hec1 (non-phospho Ser 55) blocking peptide - GTX70016-PEP from GeneTex Category Peptide Prices $199.00 Sizes 100 μg Species Human, Mouse, Rat

Hec1 (non-phospho Ser 76/77) blocking peptide - GTX70014-PEP from GeneTex Category Peptide Prices $199.00 Sizes 100 μg Species Human

Hec1 (phospho Ser 165) blocking peptide - GTX70013-PEP from GeneTex Category Peptide Prices $199.00 Sizes 100 μg Species Human, Mouse, Rat

Hec1 (phospho Ser 55) blocking peptide - GTX70017-PEP from GeneTex Category Peptide Prices $199.00 Sizes 100 μg Species Human, Mouse, Rat

Hec1 (phospho Ser 76/77) blocking peptide - GTX70015-PEP from GeneTex Category Peptide Prices $199.00 Sizes 100 μg Species Human

Hec1 blocking peptide - GTX23393-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

NDC80 Protein Lysate (APL10869) - APL10869 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

NDC80 Blocking Peptide - abx063670 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog, Monkey

HEC1 Peptide - AC21-0248-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NDC80 - H00010403-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NDC80 - H00010403-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NDC80 - H00010403-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NDC80 - H00010403-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HEC1 Peptide - 45-725P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

NDC80 fusion protein - ag8065 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

NDC80 fusion protein - ag4535 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human NDC80, His-tagged - NDC80-27986TH from Creative Biomart Category Protein Source E. coli Species Human

NDC80 Blocking Peptide - CBP2476 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Dog, Monkey

Search more