PLCB4

Gene Symbol PLCB4
Entrez Gene 5332
Alt Symbol ARCND2, PI-PLC
Species Human
Gene Type protein-coding
Description phospholipase C, beta 4
Other Description 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4|PLC-beta-4|dJ1119D9.2 (Phopholipase C, beta 4 (1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 4))|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphoinositidase C|phosphoinositide phospholipase C-beta-4|triphosphoinositide phosphodiesterase
Swissprots Q9UJQ2 Q5JYT0 Q15147 Q9BQW5 Q9BQW6 Q17R56 B7ZLK6 Q5JYT3 Q9BQW8 E2QRH8 Q5JYT4 Q5JYS9 Q5JYS8
Accessions EAX10364 EAX10365 EAX10366 EAX10367 EAX10368 EAX10369 EAX10370 Q15147 AK025027 AK054754 AK057634 AK122699 AK307482 AK307837 AL117633 AL844332 BC117458 AAI17459 BC143868 AAI43869 BG220268 BI439140 BX648680 DB270238 DN913865 DR761451 L41349 AAB02027 XM_005260724 XP_005260781 XM_005260728 XP_005260785 XM_006723568 XP_006723631 XM_006723569 XP_006723632 XM_011529251 XP_011527553 XM_011529252 XP_011527554 XM_011529253 XP_011527555 XM_011529254 XP_011527556 NM_000933 NP_000924 NM_001172646 NP_001166117 NM_182797 NP_877949
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This form has a role in retina signal transduction.
Tissue Specificity Preferentially expressed in the retina.
Top Pathways Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway, Inflammatory mediator regulation of TRP channels

PLC β4 (A-8) - sc-166131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PLC β4 (A-8): sc-166131. Western blot analysis of PLC β4 expression in ES-2 whole cell lysate.

PLC β4 (C-18) - sc-404 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PLC β4 (C-18): sc-404. Western blot analysis of PLC β4 expression in rat cerebellum extract.

PLC β4 (D-7) - sc-166133 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PLC β4 (D-7): sc-166133. Western blot analysis of PLC β4 expression in ES-2 whole cell lysate.

PLC β4 (E-1) - sc-166132 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PLC β4 (E-1): sc-166132. Western blot analysis of PLC β4 expression in ES-2 whole cell lysate.

PLC β4 (K-16) - sc-31764 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PLC β4 (H-300) - sc-20760 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PLC β4 (H-300): sc-20760. Western blot analysis of PLC β4 expression in rat cerebellum tissue extract.

PLC β4 (L-15) - sc-31765 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PLC β4 (56) - sc-136041 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal
PLC β4 (56): sc-136041. Western blot analysis of PLC β4 expression in rat pituitary tissue extract.

PLC-beta 4 Antibody - AF5128 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of DU145 human prostate carcinoma cell line, H4‑II‑E‑C3 rat hepatoma cell line, and Neuro‑2A mouse neuroblastoma cell line. PVDF membrane was probed with 1 µg/mL of Human/Mouse/Rat PLC-beta 4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5128) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for PLC-beta 4 at approximately 140 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Anti-PLCB4 (871-885) antibody produced in rabbit - SAB1100440 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PLCB4 (871-885), <B>Cat. No. SAB1100440</B>: Immunofluorescence of HUVEC cells using Anti-PLCB4 (871-885), SAB1100440 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PLCB4 (1-15) antibody produced in rabbit - SAB1100439 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PLCB4 (1-15), <B>Cat. No. SAB1100439</B>: Immunofluorescence of HUVEC cells using Anti-PLCB4 (1-15), SAB1100439 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Human/Mouse/Rat PLC-beta 4 Antibody - AF5128 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Detection of Human/Mouse/Rat PLC-beta 4 by Western Blot. Western blot shows lysates of DU145 human prostate carcinoma cell line, H4-II-E-C3 rat hepatoma cell line, and Neuro-2A mouse neuroblastoma cell line. PVDF membrane was probed with 1 µg/mL of Human/Mouse/Rat PLC-beta 4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5128) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109 ). A specific band was detected for PLC-beta 4 at approximately 140 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .
Detection of Human/Mouse/Rat PLC-beta 4 by Western Blot. Western blot shows lysates of DU145 human prostate carcinoma cell line, H4‑II‑E‑C3 rat hepatoma cell line, and Neuro‑2A mouse neuroblastoma cell line. PVDF membrane was probed with 1 µg/mL of Human/Mouse/Rat PLC-beta 4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5128) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for PLC-beta 4 at approximately 140 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

PLCB4 antibody - 70R-35323 from Fitzgerald

Host Rabbit
Clonality Polyclonal

PLCB4 antibody - orb155171 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

PLCB1 antibody - 70R-5669 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PLCB4 Antibody - abx037229 from Abbexa

Host Rabbit
Clonality Polyclonal

PLCB4 Antibody - E306199 from Enogene

Prices $275.00
Sizes 100μg/200μl

PLCB4, Polyclonal Antibody - MBS858184 from MyBioSource

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PLCB4 Antibody - DF2564 from Affinity Biosciences

Prices $220.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLCB4 Antibody A06404 - A06404 from Boster Bio

Prices $299.00
Sizes 1
Host Rabbit
Clonality Polyclonal

PLCB4 Antibody - 44841 from Signalway Antibody

Prices $189.00, $279.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of PLCB4 expression in HEK293 cells ,The lane on the left is treated with the antigen-specific peptide.

PLC-beta 4 Antibody - NBP2-58912 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PLC-beta 4 Antibody [NBP2-58912] - Staining of human cell line U-251 MG shows localization to microtubules.

Phospholipase C Beta 4, Polyclonal Antibody - MBS2033947 from MyBioSource

Prices $160.00, $320.00, $495.00
Sizes 20 µg, 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal
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