| Gene Symbol |
PLCB4
|
| Entrez Gene |
5332
|
| Alt Symbol |
ARCND2, PI-PLC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholipase C, beta 4
|
| Other Description |
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4|PLC-beta-4|dJ1119D9.2 (Phopholipase C, beta 4 (1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 4))|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphoinositidase C|phosphoinositide phospholipase C-beta-4|triphosphoinositide phosphodiesterase
|
| Swissprots |
Q9UJQ2 Q5JYT0 Q15147 Q9BQW5 Q9BQW6 Q17R56 B7ZLK6 Q5JYT3 Q9BQW8 E2QRH8 Q5JYT4 Q5JYS9 Q5JYS8
|
| Accessions |
EAX10364 EAX10365 EAX10366 EAX10367 EAX10368 EAX10369 EAX10370 Q15147 AK025027 AK054754 AK057634 AK122699 AK307482 AK307837 AL117633 AL844332 BC117458 AAI17459 BC143868 AAI43869 BG220268 BI439140 BX648680 DB270238 DN913865 DR761451 L41349 AAB02027 XM_005260724 XP_005260781 XM_005260728 XP_005260785 XM_006723568 XP_006723631 XM_006723569 XP_006723632 XM_011529251 XP_011527553 XM_011529252 XP_011527554 XM_011529253 XP_011527555 XM_011529254 XP_011527556 NM_000933 NP_000924 NM_001172646 NP_001166117 NM_182797 NP_877949
|
| Function |
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This form has a role in retina signal transduction.
|
| Tissue Specificity |
Preferentially expressed in the retina.
|
| Top Pathways |
Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway, Inflammatory mediator regulation of TRP channels
|