MAPK4

Gene Symbol	MAPK4
Entrez Gene	5596
Alt Symbol	ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase 4
Other Description	Erk3-related|MAP kinase isoform p63|MAPK 4|extracellular signal-regulated kinase 4
Swissprots	A1A4C4 P31152 Q0VG04
Accessions	EAW62976 EAW62977 P31152 AA771957 AI088913 AK293818 BAG57223 AK295058 BAG58107 AK303601 BAG64616 BC040493 BC050299 AAH50299 BC117216 AAI17217 BC143769 BX648603 HQ258629 ADR83381 X59727 CAA42411 XM_005258299 XP_005258356 XM_011526074 XP_011524376 XM_011526075 XP_011524377 XM_011526076 XP_011524378 XM_011526077 XP_011524379 XM_011526078 XP_011524380 NM_001292039 NP_001278968 NM_001292040 NP_001278969 NM_002747 NP_002738
Function	Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates to the cytoplasm following interaction with MAPKAPK5. {ECO:0000250}.
Tissue Specificity	High expression in heart and brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ERK 4 CRISPR/Cas9 KO Plasmid (h) - sc-406660 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ERK 4 HDR Plasmid (h) - sc-406660-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ERK 4 Double Nickase Plasmid (h) - sc-406660-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ERK 4 Double Nickase Plasmid (h2) - sc-406660-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ERK 4 CRISPR Activation Plasmid (h) - sc-406660-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ERK 4 CRISPR Activation Plasmid (h2) - sc-406660-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ERK 4 Lentiviral Activation Particles (h) - sc-406660-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ERK 4 Lentiviral Activation Particles (h2) - sc-406660-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ERK 4 siRNA (h) - sc-62280 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ERK 4 shRNA Plasmid (h) - sc-62280-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ERK 4 shRNA (h) Lentiviral Particles - sc-62280-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ERK4/MAPK4 RNAi - H00005596-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® siRNA - SIHK1212 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1210 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1211 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN13013 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13013 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10812 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10812

MAPK4 siRNA (Human) - CRH3766 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human MAPK4 (NM_002747.3) - SHH338039 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MAPK4(NM_002747.3) - SHH175727 from Creative biogene Category siRNA Species Reactivities Human

Human MAPK4 siRNA - orb264268 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MAPK4 shRNA Plasmid (Human) - CHH3766 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

MAPK4 miRNA 3'UTR clone - MiUTR1H-06086 from Creative biogene Species Reactivities Human

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