MAPK4

Gene Symbol MAPK4
Entrez Gene 5596
Alt Symbol ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase 4
Other Description Erk3-related|MAP kinase isoform p63|MAPK 4|extracellular signal-regulated kinase 4
Swissprots A1A4C4 P31152 Q0VG04
Accessions EAW62976 EAW62977 P31152 AA771957 AI088913 AK293818 BAG57223 AK295058 BAG58107 AK303601 BAG64616 BC040493 BC050299 AAH50299 BC117216 AAI17217 BC143769 BX648603 HQ258629 ADR83381 X59727 CAA42411 XM_005258299 XP_005258356 XM_011526074 XP_011524376 XM_011526075 XP_011524377 XM_011526076 XP_011524378 XM_011526077 XP_011524379 XM_011526078 XP_011524380 NM_001292039 NP_001278968 NM_001292040 NP_001278969 NM_002747 NP_002738
Function Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates to the cytoplasm following interaction with MAPKAPK5. {ECO:0000250}.
Tissue Specificity High expression in heart and brain.

Human MAPK4 protein fragment - ab159216 from Abcam

Category Protein
Source Wheat germ
Species Human
ab159216 on a 12.5% SDS-PAGE stained with Coomassie Blue.

MAPK4 / ERK4 Antibody Blocking Peptide - LS-E3288 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

MAPK4 / ERK4 Antibody Blocking Peptide - LS-E20486 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

MAPK4 / ERK4 Antibody Blocking Peptide - LS-E9010 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human ERK4/MAPK4 Protein - H00005596-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

ERK4/MAPK4 Peptide - P2503 from Novus Biologicals

Category Peptide
Species Human

ERK4/MAPK4 Peptide - P2485 from Novus Biologicals

Category Peptide
Species Human

MAPK4-Antibody-C-term-Blocking-Peptide - BP7298b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MAPK4-Antibody-N-term-Blocking-Peptide - BP7298a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

ERK4-Antibody-C-term-Blocking-Peptide - BP7503a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MAPK4 Blocking Peptide - 33R-1930 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

MAPK4 / ERK4 - H00005596-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

MAPK4 / ERK4 - H00005596-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

MAPK4 fusion protein - Ag22899 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Mitogen-activated protein kinase 4(MAPK4) - CSB-YP013457HU CSB-EP013457HU CSB-BP013457HU CSB-MP013457HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

MAPK4 Protein - abx163474 from Abbexa

Category Protein
Species Human, Mouse, Rat

MAPK4 / ERK4 - TP307414 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
MAPK4 / ERK4

ERK4/MAPK4 Protein - NBP1-84805PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

MAPK4 Peptide, Human - M34GP09202H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

MAPK4 peptide - orb72949 from Biorbyt

Category Peptide
Prices $238.00
Sizes 500 µg

Mitogen-activated protein kinase 4 (MAPK4), Recombinant Protein - MBS951360 from MyBioSource

Category Protein
Prices $1,385.00, $1,385.00, $1,605.00, $1,605.00, $2,315.00, $2,315.00, $2,760.00, $2,760.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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