MAPK4

Gene Symbol MAPK4
Entrez Gene 5596
Alt Symbol ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase 4
Other Description Erk3-related|MAP kinase isoform p63|MAPK 4|extracellular signal-regulated kinase 4
Swissprots A1A4C4 P31152 Q0VG04
Accessions EAW62976 EAW62977 P31152 AA771957 AI088913 AK293818 BAG57223 AK295058 BAG58107 AK303601 BAG64616 BC040493 BC050299 AAH50299 BC117216 AAI17217 BC143769 BX648603 HQ258629 ADR83381 X59727 CAA42411 XM_005258299 XP_005258356 XM_011526074 XP_011524376 XM_011526075 XP_011524377 XM_011526076 XP_011524378 XM_011526077 XP_011524379 XM_011526078 XP_011524380 NM_001292039 NP_001278968 NM_001292040 NP_001278969 NM_002747 NP_002738
Function Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates to the cytoplasm following interaction with MAPKAPK5. {ECO:0000250}.
Tissue Specificity High expression in heart and brain.

ERK 4 (Y-19) - sc-68170 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
ERK 4 (Y-19): sc-68170. Western blot analysis of ERK 4 expression in mouse heart tissue extract.

ERK 4 (N-20) - sc-68169 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ERK 4 (N-20): sc-68169. Western blot analysis of ERK 4 expression in mouse heart tissue extract.

Anti-MAPK4 antibody - ab96816 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MAPK4 antibody (ab96816) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-MAPK4 antibody - ab94617 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MAPK4 antibody (ab94617) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal heart lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-MAPK4 antibody [2D7] - ab139330 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D7
All lanes : Anti-MAPK4 antibody [2D7] (ab139330) at 1/4000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY MAPK4 cDNALysates/proteins at 35 µg per lane.

Anti-MAPK4 antibody [2F4] - ab140972 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F4
All lanes : Anti-MAPK4 antibody [2F4] (ab140972) at 1/4000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY MAPK4 cDNALysates/proteins at 5 µg per lane.

Anti-MAPK4 antibody - N-terminal - ab173310 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-MAPK4 antibody - N-terminal (ab173310) at 1/100 dilution + Mouse brain tissue lysates at 35 µg

Anti-MAPK4 / ERK4 Antibody (aa1-326) IHC-plus™ - LS-B10768 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MAPK4 / ERK4 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10768 concentration 7.5 ug/ml.

Anti-MAPK4 / ERK4 Antibody (clone 2F4) - LS-C337997 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F4
IHC of paraffin-embedded Human pancreas tissue using anti-MAPK4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-MAPK4 / ERK4 Antibody (clone 2D7) - LS-C174528 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D7
IHC of paraffin-embedded Human tonsil using anti-MAPK4 mouse monoclonal antibody.

Anti-MAPK4 / ERK4 Antibody (C-Terminus) - LS-C37298 from LifeSpan Bioscience

Prices $465.00
Sizes 250 µg
Host Sheep
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (aa527-557) - LS-C99954 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ERK4 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-MAPK4 / ERK4 Antibody (aa287-336) - LS-C111919 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MAPK4 antibody LS-C111919 Western blot of Fetal Heart lysate.

Anti-MAPK4 / ERK4 Antibody (aa67-94, AP) - LS-C215725 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (clone 666316) - LS-C150126 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 666316
Detection of ERK4. Lysates from human LnCap, human Raji, and mouse TS1 cells were resolved by SDS-PAGE, transferred to an Immobilon-P membrane, and immunoblotted with 2 ug/ml anti-ERK4. A one minute exposure to film is shown.

Anti-MAPK4 / ERK4 Antibody (aa537-566) - LS-C100885 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-MAPK4 Antibody in Jurkat cell line lysates (35 ug/lane). MAPK4(arrow) was detected using the purified antibody.

Anti-MAPK4 / ERK4 Antibody (aa67-94, APC) - LS-C215726 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (aa67-94, Biotin) - LS-C215727 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (aa67-94, FITC) - LS-C215728 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (aa72-101) - LS-C100884 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MAPK4 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-MAPK4 / ERK4 Antibody (aa67-94, Azide-free, HRP) - LS-C215729 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (aa67-94, PE) - LS-C215730 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (C-Terminus, AP) - LS-C219987 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (C-Terminus, APC) - LS-C219986 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAPK4 / ERK4 Antibody (C-Terminus, Biotin) - LS-C219989 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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