Gck

Gene Symbol	Gck
Entrez Gene	103988
Alt Symbol	GLK, Gk, Gls006, HK4, HKIV, HXKP, Hlb62, MODY2
Species	Mouse
Gene Type	protein-coding
Description	glucokinase
Other Description	HK IV|hexokinase 4|hexokinase type IV|hexokinase-4|hexokinase-D
Swissprots	P52791 P52792
Accessions	AAC42074 BAJ19146 BAJ19147 BAJ19148 BAJ19149 CBF63183 CBU88059 EDL40567 EDL40568 P52792 AK142698 BC011139 AAH11139 L38988 AAB00359 L38990 AAB00360 M58755 AAA37703 XM_006514443 XP_006514506 XM_006514444 XP_006514507 NM_001287386 NP_001274315 NM_010292 NP_034422
Function	Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Under low glucose concentrations, GCK associates with GKRP and the inactive complex is recruited to the hepatocyte nucleus. {ECO:0000250}.
Tissue Specificity	Pancreas, anterior pituitary (isoform 1) and liver (isoform 2).
Top Pathways	Glucagon signaling pathway, Central carbon metabolism in cancer, Prolactin signaling pathway, Insulin signaling pathway, Glycolysis / Gluconeogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Glucokinase (GCK) - RPA667Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Glucokinase (GCK) - RPA667Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Glucokinase(Gck) - CSB-YP009319MO CSB-EP009319MO CSB-BP009319MO CSB-MP009319MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse GCK Protein - GCK-6265M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Recombinant Glucokinase (GCK) - RPU52011 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Mouse

GCK Recombinant Protein (OPCD03463) - OPCD03463 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Glucokinase, Recombinant Protein - MBS2033410 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

Glucokinase, Recombinant Protein - MBS2031039 from MyBioSource Category Protein Prices $195.00, $420.00, $650.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

Glucokinase (Gck), Recombinant Protein - MBS954827 from MyBioSource Category Protein Prices $1,245.00, $1,245.00, $1,465.00, $1,465.00, $2,030.00, $2,030.00, $2,495.00, $2,495.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

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