Gck

Gene Symbol Gck
Entrez Gene 103988
Alt Symbol GLK, Gk, Gls006, HK4, HKIV, HXKP, Hlb62, MODY2
Species Mouse
Gene Type protein-coding
Description glucokinase
Other Description HK IV|hexokinase 4|hexokinase type IV|hexokinase-4|hexokinase-D
Swissprots P52791 P52792
Accessions AAC42074 BAJ19146 BAJ19147 BAJ19148 BAJ19149 CBF63183 CBU88059 EDL40567 EDL40568 P52792 AK142698 BC011139 AAH11139 L38988 AAB00359 L38990 AAB00360 M58755 AAA37703 XM_006514443 XP_006514506 XM_006514444 XP_006514507 NM_001287386 NP_001274315 NM_010292 NP_034422
Function Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Under low glucose concentrations, GCK associates with GKRP and the inactive complex is recruited to the hepatocyte nucleus. {ECO:0000250}.
Tissue Specificity Pancreas, anterior pituitary (isoform 1) and liver (isoform 2).
Top Pathways Glucagon signaling pathway, Central carbon metabolism in cancer, Prolactin signaling pathway, Insulin signaling pathway, Glycolysis / Gluconeogenesis

Glucokinase (GCK), Polyclonal Antibody - MBS2003275 from MyBioSource

Prices $320.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Glucokinase (GCK), Polyclonal Antibody - MBS2001577 from MyBioSource

Prices $220.00, $290.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Glucokinase (GCK), Polyclonal Antibody - MBS2017529 from MyBioSource

Prices $385.00
Sizes 100 µg
Clonality Polyclonal

Polyclonal Antibody to Glucokinase (GCK) - PAA667Mu01 from Cloud-clone

Host Rabbit
Clonality Polyclonal

Polyclonal Antibody to Glucokinase (GCK) - PAA667Mu02 from Cloud-clone

Host Rabbit
Clonality Polyclonal

Glucokinase antibody - 70R-49785 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

anti-GCK (Glucokinase) antibody - ARG20051 from Arigo Biolaboratories

Host Rabbit
Clonality Polyclonal

anti-GCK (Glucokinase) antibody - ARG20052 from Arigo Biolaboratories

Host Rabbit
Clonality Polyclonal

Glucokinase (GCK) Polyclonal Antibody - CAU27417 from Biomatik

Prices $103.00, $240.00, $343.00, $550.00
Sizes 10 μg, 50 μg, 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

Glucokinase (GCK), Polyclonal Antibody - MBS2045732 from MyBioSource

Prices $835.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Glucokinase (GCK), Polyclonal Antibody - MBS2045733 from MyBioSource

Prices $350.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Glucokinase (GCK), Polyclonal Antibody - MBS2045734 from MyBioSource

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Glucokinase (GCK), Polyclonal Antibody - MBS2045735 from MyBioSource

Prices $565.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Glucokinase (GCK), Polyclonal Antibody - MBS2045736 from MyBioSource

Prices $350.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Glucokinase (GCK), Polyclonal Antibody - MBS2045737 from MyBioSource

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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