AQR

Gene Symbol AQR
Entrez Gene 9716
Alt Symbol IBP160, fSAP164
Species Human
Gene Type protein-coding
Description aquarius intron-binding spliceosomal factor
Other Description aquarius homolog|functional spliceosome-associated protein 164|intron-binding protein aquarius|intron-binding protein of 160 kDa
Swissprots A5YKK3 A0JP17 O60306 Q6IRU8 Q2YDX9 Q6PIC8
Accessions EAW92319 EAW92320 EAW92321 O60306 AB011132 BAA25486 AK001173 AK291615 BAF84304 AK315815 BAF98706 AL703893 BC027452 BC036913 AAH36913 BC070379 AAH70379 BC108262 AAI08263 BC127111 AAI27112 BC127112 AAI27113 BX647820 BX648611 EF553519 ABQ66265 NM_014691 NP_055506
Function Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. {ECO:0000269|PubMed:16949364}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16949364}. Note=Localizes to speckle-like regions of the nucleoplasm. {ECO:0000269|PubMed:16949364}.
Top Pathways Spliceosome

AQR CRISPR/Cas9 KO Plasmid (h) - sc-411323 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AQR HDR Plasmid (h) - sc-411323-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AQR Double Nickase Plasmid (h) - sc-411323-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AQR Double Nickase Plasmid (h2) - sc-411323-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AQR CRISPR Activation Plasmid (h) - sc-411323-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AQR CRISPR Activation Plasmid (h2) - sc-411323-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AQR Lentiviral Activation Particles (h) - sc-411323-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AQR Lentiviral Activation Particles (h2) - sc-411323-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AQR siRNA (h) - sc-90163 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AQR shRNA Plasmid (h) - sc-90163-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AQR shRNA (h) Lentiviral Particles - sc-90163-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU016831 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN3380 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3380 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03327 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03327

AQR siRNA (Human) - CRH6484 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AQR - MBS8228679 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Aqr (NM_014691.2) - SHH238954 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AQR(NM_014691.2) - SHG067573 from Creative biogene

Category siRNA
Species Reactivities Human

Human AQR siRNA - orb266986 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AQR shRNA Plasmid (Human) - CHH6484 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AQR miRNA 3'UTR clone - MiUTR1H-00505 from Creative biogene

Species Reactivities Human
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