Gene Symbol | AQR |
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Entrez Gene | 9716 |
Alt Symbol | IBP160, fSAP164 |
Species | Human |
Gene Type | protein-coding |
Description | aquarius intron-binding spliceosomal factor |
Other Description | aquarius homolog|functional spliceosome-associated protein 164|intron-binding protein aquarius|intron-binding protein of 160 kDa |
Swissprots | A5YKK3 A0JP17 O60306 Q6IRU8 Q2YDX9 Q6PIC8 |
Accessions | EAW92319 EAW92320 EAW92321 O60306 AB011132 BAA25486 AK001173 AK291615 BAF84304 AK315815 BAF98706 AL703893 BC027452 BC036913 AAH36913 BC070379 AAH70379 BC108262 AAI08263 BC127111 AAI27112 BC127112 AAI27113 BX647820 BX648611 EF553519 ABQ66265 NM_014691 NP_055506 |
Function | Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. {ECO:0000269|PubMed:16949364}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16949364}. Note=Localizes to speckle-like regions of the nucleoplasm. {ECO:0000269|PubMed:16949364}. |
Top Pathways | Spliceosome |
AQR (C-15) - sc-167106 from Santa Cruz Biotechnology
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AQR (P-20) - sc-167109 from Santa Cruz Biotechnology
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Anti-IBP160 antibody - ab133810 from Abcam
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Anti-AQR Antibody (aa500-550) - LS-C289277 from LifeSpan Bioscience
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Anti-AQR Antibody (C-Terminus) - LS-C151713 from LifeSpan Bioscience
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Anti-AQR Antibody (aa1435-1485) - LS-C286902 from LifeSpan Bioscience
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Anti-AQR Antibody (aa1435-1485) - LS-C289279 from LifeSpan Bioscience
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Intron-Binding Protein Of 160 KDa Antibody - NBP2-23607 from Novus Biologicals
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IBP160 Polyclonal Antibody - bs-15530R from Bioss
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AQR Antibody - C-terminal region (ARP64428_P050) - ARP64428_P050 from Aviva Systems Biology
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Anti -AQR (Aquarius, Intron-binding Protein Aquarius, IBP160, fSAP164) - 209571 from USBiological Life Science
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AQR Polyclonal Antibody - A6011 from ABclonal
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AQR antibody - orb12794 from Biorbyt
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IBP160 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15530R-A350 from Bioss
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IBP160 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15530R-A488 from Bioss
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IBP160 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15530R-A555 from Bioss
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IBP160 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15530R-A647 from Bioss
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IBP160 Polyclonal Antibody, Cy3 Conjugated - bs-15530R-Cy3 from Bioss
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IBP160 Polyclonal Antibody, Cy5 Conjugated - bs-15530R-Cy5 from Bioss
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IBP160 Polyclonal Antibody, Cy5.5 Conjugated - bs-15530R-Cy5.5 from Bioss
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IBP160 Polyclonal Antibody, Cy7 Conjugated - bs-15530R-Cy7 from Bioss
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IBP160 Polyclonal Antibody, FITC Conjugated - bs-15530R-FITC from Bioss
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IBP160 Polyclonal Antibody, Biotin Conjugated - bs-15530R-Biotin from Bioss
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IBP160 Polyclonal Antibody, HRP Conjugated - bs-15530R-HRP from Bioss
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AQR Antibody - abx004620 from Abbexa
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