Gene Symbol | AQR |
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Entrez Gene | 9716 |
Alt Symbol | IBP160, fSAP164 |
Species | Human |
Gene Type | protein-coding |
Description | aquarius intron-binding spliceosomal factor |
Other Description | aquarius homolog|functional spliceosome-associated protein 164|intron-binding protein aquarius|intron-binding protein of 160 kDa |
Swissprots | A5YKK3 A0JP17 O60306 Q6IRU8 Q2YDX9 Q6PIC8 |
Accessions | EAW92319 EAW92320 EAW92321 O60306 AB011132 BAA25486 AK001173 AK291615 BAF84304 AK315815 BAF98706 AL703893 BC027452 BC036913 AAH36913 BC070379 AAH70379 BC108262 AAI08263 BC127111 AAI27112 BC127112 AAI27113 BX647820 BX648611 EF553519 ABQ66265 NM_014691 NP_055506 |
Function | Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. {ECO:0000269|PubMed:16949364}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16949364}. Note=Localizes to speckle-like regions of the nucleoplasm. {ECO:0000269|PubMed:16949364}. |
Top Pathways | Spliceosome |
AQR Antibody Blocking Peptide - LS-E23489 from LifeSpan Bioscience
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AQR-Antibody-Center-Blocking-Peptide - BP9390c from Abgent, a WuXi AppTec company
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AQR fusion protein - ag17810 from Proteintech Group
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AQR fusion protein - ag17894 from Proteintech Group
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Recombinant Human Intron-binding protein aquarius(AQR) ,partial - CSB-YP001974HU CSB-EP001974HU CSB-BP001974HU CSB-MP001974HU from Cusabio
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AQR - TP320742 from Acris Antibodies
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AQR Peptide, Human - M34GP00820H from Creative Peptides
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Intron-binding protein aquarius (AQR), partial, Recombinant Protein - MBS1008754 from MyBioSource
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Intron-Binding Protein Of 160 KDa Recombinant Protein Antigen - NBP2-57794PEP from Novus Biologicals
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Intron-Binding Protein Of 160 KDa Recombinant Protein Antigen - NBP2-55806PEP from Novus Biologicals
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