Otub1

Gene Symbol Otub1
Entrez Gene 107260
Alt Symbol AI850305
Species Mouse
Gene Type protein-coding
Description OTU domain, ubiquitin aldehyde binding 1
Other Description OTU domain-containing ubiquitin aldehyde-binding protein 1|deubiquitinating enzyme OTUB1|otubain 1|otubain-1|ubiquitin thioesterase OTUB1|ubiquitin-specific-processing protease OTUB1
Swissprots Q3ULV9 Q7TQI3 Q8C326 Q8R5F2 Q3V408
Accessions EDL33291 Q7TQI3 AK027996 BAE20433 AK087195 AK140070 BAE24227 AK145273 BAE26339 AK145970 BAE26795 AK191684 AK217174 BC022575 AAH22575 BC054410 AAH54410 NM_134150 NP_598911
Function Hydrolase that can specifically remove compared to 'Lys- 48'-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen. Acts via its interaction with RNF128/GRAIL. Surprisingly, it regulates RNF128-mediated ubiquitination, but does not deubiquitinate polyubiquitinated RNF128. Deubiquitinates estrogen receptor alpha (ESR1). Mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains, but not 'Lys-63'-linked polyubiquitin chains. Not able to cleave di-ubiquitin. Also capable of removing NEDD8 from NEDD8 conjugates, but with a much lower preference compared to 'Lys-48'- linked ubiquitin. {ECO:0000269|PubMed:14661020}.
Subcellular Location Cytoplasm {ECO:0000250}.

OTUB1 antibody, Internal - GTX88681 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-OTUB1 antibody, Internal used in Western blot. GTX88681

OTUB1 antibody - orb19923 from Biorbyt

Prices $408.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
orb19923 (0.05ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Otubain 1 Antibody - abx100621 from Abbexa

Host Rabbit
Clonality Polyclonal

Anti-Otubain 1 (OTUB1) - 20-5577 from ARP American Research Products

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-OTUB1 antibody - STJ71615 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

Otubain 1 - 280 003 from Synaptic Systems

Host Rabbit
Clonality Polyclonal
Cat. No. 280 003 antibody dilution: 1 : 1000 sample: rat spleen homogenate

OTUB1 Polyclonal Antibody - PA5-18960 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot staining of Mouse Brain lysate using PA5-18960 at a concentration of 0.05 ug/ml, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.

Polyclonal Antibody to Otubain 1 (OTUB1) - PAL838Mu01 from Cloud-clone

Host Rabbit
Clonality Polyclonal

Biotin-Linked Antibody to Otubain 1 (OTUB1) - PAL838Mu71 from Cloud-clone

Host Rabbit
Clonality Polyclonal

FITC-Linked Antibody to Otubain 1 (OTUB1) - PAL838Mu81 from Cloud-clone

Host Rabbit
Clonality Polyclonal

anti-OTUB1 antibody - ARG64598 from Arigo Biolaboratories

ARG64598 anti-OTUB1 antibody WB image Western Blot: Mouse Brain lysate (35 µg protein in RIPA buffer) stained with ARG64598 anti-OTUB1 antibody at 0.05 µg/ml dilution.

Otubain 1 (OTUB1) Polyclonal Antibody - CAU21397 from Biomatik

Prices $126.00, $294.00, $420.00, $672.00
Sizes 10 μg, 50 μg, 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

OTUB1 antibody - GTX133353 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal

OTUB1 antibody - GTX133347 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal

OTUB1, Polyclonal Antibody Pair - MBS7041831 from MyBioSource

Prices $735.00
Sizes 1 pair (Sufficient for 5x96 well plates)
Host Rabbit
Clonality Polyclonal

Otubain 1 (OTUB1), Polyclonal Antibody - MBS2083323 from MyBioSource

Prices $1,005.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Otubain 1 (OTUB1), Polyclonal Antibody - MBS2083324 from MyBioSource

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Otubain 1 (OTUB1), Polyclonal Antibody - MBS2083325 from MyBioSource

Prices $520.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Otubain 1 (OTUB1), Polyclonal Antibody - MBS2083326 from MyBioSource

Prices $685.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Otubain 1 (OTUB1), Polyclonal Antibody - MBS2083327 from MyBioSource

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-OTUB1 Goat Antibody - EB08653 from ARP American Research Products

Prices $315.00
Sizes 100 µg
Clonality Polyclonal

OTUB1 Polyclonal Antibody - A10313 from ARP American Research Products

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Clonality Polyclonal
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