Shh

Gene Symbol	Shh
Entrez Gene	20423
Alt Symbol	9530036O11Rik, Dsh, Hhg1, Hx, Hxl3, M100081
Species	Mouse
Gene Type	protein-coding
Description	sonic hedgehog
Other Description	HHG-1|hemimelic extra toes|short digits|sonic hedgehog protein
Swissprots	Q62226
Accessions	EDL37231 Q62226 AK077688 BAC36956 BC063087 AAH63087 EU664592 ACD69663 X76290 CAA53922 XM_006535648 XP_006535711 XM_006535649 XP_006535712 NM_009170 NP_033196
Function	Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior- posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO. {ECO:0000269|PubMed:14687547, ECO:0000269|PubMed:7736596}.
Subcellular Location	Sonic hedgehog protein C-product: Secreted, extracellular space. Note=The C-terminal peptide diffuses from the cell.
Tissue Specificity	Expressed in a number of embryonic tissues including the notochord, ventral neural tube, floor plate, lung bud, zone of polarizing activity and posterior distal mesenchyme of limbs. In the adult, expressed in lung and neural retina.
Top Pathways	Hedgehog signaling pathway, Basal cell carcinoma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Shh-N Mouse ELISA Kit - ab155451 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 5 pg/ml Range 4.1 pg/ml - 1000 pg/ml

Shh-N Mouse ELISA Kit - ab155450 from Abcam Category ELISA Kit Prices $531.00 Sizes 1 x 96 tests Sensitivity < 5 pg/ml Range 5 pg/ml - 1200 pg/ml

Mouse Shh-N ELISA Kit - RAB0432 from Sigma-Aldrich Category ELISA Kit Prices $666.00 Sizes 1 kt

Mouse Shh-N ELISA Kit - RAB0431 from Sigma-Aldrich Category ELISA Kit Prices $438.50 Sizes 1 kt

Hemopexin (HPX), Mouse, ELISA Kit - CSB-EL010723MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Sonic hedgehog protein (SHH), Mouse, ELISA Kit - CSB-EL021266MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Sonic hedgehog protein, Shh, Mouse, ELISA Kit - E1831m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Mouse ShhN ELISA (For Lysates) - ELM-ShhN-CL from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 5 pg/ml

Mouse ShhN ELISA - ELM-ShhN from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 5 pg/ml Range 5 pg/ml - 1000 pg/ml

Mouse SHH ELISA Kit - MS0111 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

SHH, ELISA Kit - MBS2506137 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625--1000pg/mL

Mouse Sonic Hedgehog/Shh N-Terminus ELISA Kit - DEIA2938 from Creative Diagnostics Category ELISA Kit Sensitivity 1.22 pg/mL Range 0.032 - 2.37 pg/mL

Mouse SHH(Hedgehog Homolog, Sonic) ELISA Kit - E-EL-M0623 from Elabscience Category ELISA Kit Sensitivity 9.38 pg/mL Range 15.63—1000 pg/mL

Mouse SHH (Hedgehog Homolog, Sonic) CLIA Kit - E-CL-M0378 from Elabscience Category CLIA Kit Sensitivity 4.69 pg/mL Range Average Recovery (%)

sonic hedgehog homolog (Drosophila) , ELISA Kit - MBS907964 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

Mouse Sonic hedgehog protein(SHH) ELISA kit - CSB-EL021266MO from Cusabio Category ELISA Kit Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

Mouse Hedgehog Homolog, Sonic ELISA - E03S0104 from BlueGene Biotech Category ELISA Kit

Mouse SHH(Hedgehog Homolog, Sonic) ELISA Kit - E-EL-M0623 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 9.38 pg/mL Range 15.63~1000 pg/mL

Mouse COL1*(Collagen Type I)* CLIA Kit - E-CL-M0212 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 9.375ng/mL Range 15.625-1000ng/mL

Mouse SHH (Hedgehog Homolog, Sonic) CLIA Kit - E-CL-M0378 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

SHH (Hedgehog Homolog, Sonic), CLIA Kit - MBS2532613 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 4.688pg/mL Range 7.813-500pg/mL

Mouse Sonic hedgehog protein (SHH) ELISA Kit - EKC37849 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

SHH - EKM2720 from Nordic BioSite Sensitivity 9.375pg/ml Range 15.625--1000pg/ml

Mouse ShhN ELISA - ELM-ShhN-1 from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,560.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Mouse ShhN ELISA (For Lysates) - ELM-ShhN-CL-1 from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,560.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

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