Ephb1

Gene Symbol	Ephb1
Entrez Gene	270190
Alt Symbol	9330129L11, AW488255, C130099E04Rik, Cek6, ENSMUSG00000074119, Elk, Elkh, Hek6, Net
Species	Mouse
Gene Type	protein-coding
Description	Eph receptor B1
Other Description	ephrin type-B receptor 1
Swissprots	Q6PG23 Q8CBF3 B1B1C2 Q8CBE2 Q3UY27
Accessions	EDL21046 EDL21047 Q8CBF3 AK033966 AK036148 BAC29320 AK036211 BAC29348 AK039530 BAC30375 AK082061 BAC38401 AK135018 BAE22386 AK163703 BC057301 AAH57301 NM_001168296 NP_001161768 NM_173447 NP_775623
Function	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formatio
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Early endosome membrane {ECO:0000250}. Cell projection, dendrite {ECO:0000269|PubMed:14691139}.
Tissue Specificity	Expressed in neural stem and progenitor cells in the dentate gyrus. {ECO:0000269|PubMed:18057206}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse-Ephb1-Antibody-Center - AP20899a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Mouse-Ephb1-Antibody-Center - AP20937a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

EphB1-extracellular-Antibody - AG1432 from Abgent, a WuXi AppTec company Prices $375.00, $475.00, $575.00 Sizes 25 µl, 50 µl, 200 µl Host Rabbit Clonality Polyclonal

Mouse-Ephb1-Antibody-Center - AP20994a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

EPHB1/2 antibody (Tyr594/604) - 70R-33572 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

EPHB antibody - 70R-32645 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti -EphB1 (EPH-related Receptor Tyrosine Kinase Ligand 2 homolog, ELK homolog) - 227441 from USBiological Life Science Host Hamster Clonality Monoclonal Clone EfrnB1

EPHB1/2 antibody - 70R-33573 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

EPHB1/2/3 antibody - 70R-35821 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Ephrin B1, Monoclonal Antibody - MBS603490 from MyBioSource Prices $565.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6A74

NET - 260 003 from Synaptic Systems Host Rabbit Clonality Polyclonal

Ephrin B1, Polyclonal Antibody - MBS615633 from MyBioSource Prices $615.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Ephrin Receptor 1 - MBS540021 from MyBioSource Prices $250.00, $290.00, $365.00, $495.00, $495.00 Sizes 100 µl antigenic peptide, 0.1-0.15 ml wb control, 200 µl affinity purified, 200 µl biotin, 200 µl fitc Host Rabbit Clonality Polyclonal

Ephrin Receptor B1 Antibody - EPHBR1-101AP from FabGennix Prices $265.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Ephb1 Antibody - middle region (OAAB18859) - OAAB18859 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Ephb1 Antibody - middle region (OAAB18897) - OAAB18897 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Ephb1 Antibody - middle region (OAAB18954) - OAAB18954 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

EPHB1/2 antibody - 70R-51798 from Fitzgerald Prices $475.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

NET antibody - 70R-51529 from Fitzgerald Prices $475.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

EPHB1/2/3, Polyclonal Antibody - MBS5301125 from MyBioSource Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Ephb1, Polyclonal Antibody - MBS9203757 from MyBioSource Prices $155.00, $340.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Ephb1, Polyclonal Antibody - MBS9211026 from MyBioSource Prices $155.00, $340.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Ephb1, Polyclonal Antibody - MBS9207704 from MyBioSource Prices $155.00, $340.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

EPHB1 antibody - TA328806 from Acris Antibodies Prices $435.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Ephb1 Antibody (F52840) - F52840 from NSJ Bioreagent Prices $125.00, $299.00 Sizes 80 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide), 400 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide) Host Rabbit Clonality Polyclonal

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