EME1

Gene Symbol	EME1
Entrez Gene	146956
Alt Symbol	MMS4L, SLX2A
Species	Human
Gene Type	protein-coding
Description	essential meiotic structure-specific endonuclease 1
Other Description	MMS4 homolog|SLX2 structure-specific endonuclease subunit homolog A|crossover junction endonuclease EME1|essential meiotic endonuclease 1 homolog 1|essential meiotic endonuclease 1 homolog 2|hMMS4|homolog of yeast EME1 endonuclease
Swissprots	Q96N62 Q96AY2
Accessions	EAW94617 EAW94618 EAW94619 EAW94620 EAW94621 Q96AY2 AK021607 AK055926 BAB71047 AK308275 BC016470 AAH16470 DA006645 DB245967 DQ578819 JF432239 ADZ15456 XM_005257081 XP_005257138 XM_011524392 XP_011522694 XM_011524393 XP_011522695 XM_011524394 XP_011522696 XM_011524395 XP_011522697 XM_011524396 XP_011522698 XR_934390 XR_934392 XR_934393 NM_001166131 NP_001159603 NM_152463 NP_689676
Function	Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'- flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. {ECO:0000269|PubMed:12686547, ECO:0000269|PubMed:12721304, ECO:0000269|PubMed:14617801, ECO:0000269|PubMed:17289582}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:14617801}. Note=Recruited to regions of DNA damage in S-phase cells.
Top Pathways	Homologous recombination, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Crossover junction endonuclease EME1 (EME1), Human, ELISA Kit - E01C2284 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7205143 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7200832 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7248961 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7251778 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7203153 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7225175 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7206036 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7202201 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7226298 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7245523 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Crossover junction endonuclease EME1 (EME1), ELISA Kit - MBS7240437 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human EME1 ELISA Kit - E010257 from Biobool Category ELISA Kit

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