SELK

Gene Symbol	SELK
Entrez Gene	58515
Alt Symbol	HSPC030, HSPC297, SelK
Species	Human
Gene Type	protein-coding
Description	selenoprotein K
Other Description	-
Swissprots	Q8IZQ3 Q9P085 Q9Y6D0
Accessions	EAW65301 Q9Y6D0 AF085359 AAD40194 AF161415 AAF28975 AF537132 AAN61473 AK123406 AK289594 BAF82283 BC013162 AAH13162 BM762385 NM_021237 NP_067060
Function	Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration. Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins. Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation. Plays a role in protection of cells from ER stress- induced apoptosis. Protects cells from oxidative stress when overexpressed in cardiomyocytes. {ECO:0000269|PubMed:16962588, ECO:0000269|PubMed:20692228, ECO:0000269|PubMed:22016385}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
Tissue Specificity	Highly expressed in heart. {ECO:0000269|PubMed:16962588}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Selenoprotein K CRISPR/Cas9 KO Plasmid (h) - sc-407002 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K HDR Plasmid (h) - sc-407002-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K Double Nickase Plasmid (h) - sc-407002-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K Double Nickase Plasmid (h2) - sc-407002-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K CRISPR Activation Plasmid (h) - sc-407002-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K CRISPR Activation Plasmid (h2) - sc-407002-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K Lentiviral Activation Particles (h) - sc-407002-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K Lentiviral Activation Particles (h2) - sc-407002-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K siRNA (h) - sc-78353 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Selenoprotein K shRNA Plasmid (h) - sc-78353-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Selenoprotein K shRNA (h) Lentiviral Particles - sc-78353-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU110051 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19054 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19054 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02985 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02985

SELK siRNA (Human) - CRJ1741 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SELK RNAi - H00058515-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

SELK - MBS8204178 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Selenoprotein K CRISPR/Cas9 KO Plasmid (h2) - sc-407002-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein K HDR Plasmid (h2) - sc-407002-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human SELK (NM_021237.3) - SHH404084 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human SELK(NM_021237.3) - SHR212988 from Creative biogene Category siRNA Species Reactivities Human

Human SELK siRNA - orb272242 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SELK shRNA Plasmid (Human) - CHJ1741 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

SELK miRNA 3'UTR clone - MiUTR1H-09241 from Creative biogene Species Reactivities Human

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