SELK

Gene Symbol	SELK
Entrez Gene	58515
Alt Symbol	HSPC030, HSPC297, SelK
Species	Human
Gene Type	protein-coding
Description	selenoprotein K
Other Description	-
Swissprots	Q8IZQ3 Q9P085 Q9Y6D0
Accessions	EAW65301 Q9Y6D0 AF085359 AAD40194 AF161415 AAF28975 AF537132 AAN61473 AK123406 AK289594 BAF82283 BC013162 AAH13162 BM762385 NM_021237 NP_067060
Function	Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration. Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins. Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation. Plays a role in protection of cells from ER stress- induced apoptosis. Protects cells from oxidative stress when overexpressed in cardiomyocytes. {ECO:0000269|PubMed:16962588, ECO:0000269|PubMed:20692228, ECO:0000269|PubMed:22016385}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
Tissue Specificity	Highly expressed in heart. {ECO:0000269|PubMed:16962588}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SELK full length protein - ab163689 from Abcam Category Protein Source Wheat germ Species Human

Human SELK protein fragment - ab163690 from Abcam Category Protein Source Wheat germ Species Human

SELK / Selenoprotein K Antibody Blocking Peptide - LS-E2553 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SELK / Selenoprotein K Antibody Blocking Peptide - LS-E31312 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human SELK Protein - H00058515-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SELK Protein - H00058515-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SELK-Antibody-Center-Blocking-peptide - BP13595c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Selenoprotein K (SELK) - H00058515-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Selenoprotein K (SELK) - H00058515-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Selenoprotein K (SELK) - H00058515-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Selenoprotein K (SELK) - H00058515-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Selenoprotein K (SELK) (C-term) Control Peptide - AP55499CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SELK Peptide - 6975P from ProSci Category Peptide Species Human

SELK fusion protein - ag3143 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SELK Recombinant Protein Antigen - NBP1-86120PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SELK Peptide, Human - M34GP13969H from Creative Peptides Category Peptide Source Synthetic. Species Human

Selenoprotein K (SELK), Recombinant Protein - MBS1475285 from MyBioSource Category Protein Prices $825.00, $825.00, $1,050.00, $1,050.00, $1,175.00, $1,175.00, $1,630.00, $1,630.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

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