Gene Symbol | MC4R |
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Entrez Gene | 4160 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | melanocortin 4 receptor |
Other Description | MC4-R|melanocortin receptor 4 |
Swissprots | Q16317 B2RAC3 P32245 Q3MIJ6 |
Accessions | AAA35791 AAB33341 AAO92061 ABK35297 ABK35298 ABK35299 ABK35300 AFV34058 AFV34059 AFV34060 AFV34061 AFV34062 EAW63105 P32245 AK314130 BAG36820 BC069172 AAH69172 BC101802 AAI01803 BC111992 AAI11993 DA362673 NM_005912 NP_005903 |
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). {ECO:0000269|PubMed:12646665}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Brain, placental, and gut tissues. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human MC4 Receptor protein fragment - ab112318 from Abcam
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MC4 Receptor peptide - ab77324 from Abcam
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Mouse MC4 Receptor peptide - ab78212 from Abcam
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MC4R / Melanocortin 4 Receptor Antibody Blocking Peptide - LS-E28906 from LifeSpan Bioscience
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MC4R / Melanocortin 4 Receptor Antibody Blocking Peptide - LS-E23073 from LifeSpan Bioscience
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MC4R / Melanocortin 4 Receptor Antibody Blocking Peptide - LS-E28104 from LifeSpan Bioscience
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MC4R / Melanocortin 4 Receptor Antibody Blocking Peptide - LS-E28105 from LifeSpan Bioscience
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MC4R / Melanocortin 4 Receptor Antibody Blocking Peptide - LS-E28088 from LifeSpan Bioscience
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MC4R / Melanocortin 4 Receptor Antibody Blocking Peptide - LS-E30714 from LifeSpan Bioscience
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Melanocortin-4 R Partial Recombinant Protein - H00004160-Q01 from Novus Biologicals
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MC4R-Antibody-N-term-Blocking-peptide - BP10970a from Abgent, a WuXi AppTec company
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MC4 Receptor Peptide - AC21-2971-P from Abcore
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MC4-R - H00004160-G01 from Acris Antibodies
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MC4-R - H00004160-Q01-10 from Acris Antibodies
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MC4-R - H00004160-Q01-25 from Acris Antibodies
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MC4-R Control Peptide - AP30546CP-N from Acris Antibodies
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MC4R Peptide - 5199P from ProSci
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Recombinant Human MC4R - MC4R-29453TH from Creative Biomart
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MC4 Receptor Blocking Peptide - CBP1725 from Cohesion Biosciences
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MC4-R (E315) Peptide - BS2811P from Bioworld Technology
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Recombinant Human Melanocortin-4 R Protein - H00004160-G01 from Novus Biologicals
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MC4-R - TP311026 from Acris Antibodies
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MC4R, Peptide - MBS428085 from MyBioSource
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Melanocortin-4 R Recombinant Protein Antigen - NBP1-87567PEP from Novus Biologicals
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ChemiSCREEN™ Human MC 4 Melanocortin Receptor Membrane Preparation - HTS105M from EMD Millipore
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