F12

Gene Symbol F12
Entrez Gene 2161
Alt Symbol HAE3, HAEX, HAF
Species Human
Gene Type protein-coding
Description coagulation factor XII (Hageman factor)
Other Description Hageman factor|beta-factor XIIa part 1|beta-factor XIIa part 2|coagulation factor XII|coagulation factor XIIa heavy chain|coagulation factor XIIa light chain
Swissprots P78339 P00748
Accessions AAB51203 AAB51204 AAB51205 AAB51206 AAB51207 AAB59490 AAB59491 AAM97932 CAK18991 EAW85002 EAW85003 EAW85004 EAW85005 P00748 AB095845 BAC23095 BC012390 AAH12390 BC168381 AAI68381 BE139501 BT007350 AAP36014 M11723 AAA51986 M13147 AAA70224 M31315 AAA70225 XM_011534461 XP_011532763 XM_011534462 XP_011532764 NM_000505 NP_000496
Function Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. {ECO:0000269|PubMed:21304106}.
Subcellular Location Secreted.
Top Pathways Complement and coagulation cascades

Factor XII CRISPR/Cas9 KO Plasmid (h) - sc-409611 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XII HDR Plasmid (h) - sc-409611-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XII Double Nickase Plasmid (h) - sc-409611-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XII Double Nickase Plasmid (h2) - sc-409611-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XII CRISPR Activation Plasmid (h) - sc-409611-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XII CRISPR Activation Plasmid (h2) - sc-409611-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XII Lentiviral Activation Particles (h) - sc-409611-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XII Lentiviral Activation Particles (h2) - sc-409611-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XII siRNA (h) - sc-62290 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor XII shRNA Plasmid (h)-SH - sc-62290-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor XII shRNA (h) Lentiviral Particles - sc-62290-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor XII heavy chain RNAi - H00002161-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU018001 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1728 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1728 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

F12 siRNA (Human) - CRH1503 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

F12 - MBS8222196 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human F12 (NM_000505.3) - SHH288393 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human F12(NM_000505.3) - SHH043287 from Creative biogene

Category siRNA
Species Reactivities Human

Human F12 siRNA - orb262005 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

F12 shRNA Plasmid (Human) - CHH1503 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

F12 miRNA 3'UTR clone - MiUTR1H-03360 from Creative biogene

Species Reactivities Human
Search more