F12

Gene Symbol	F12
Entrez Gene	2161
Alt Symbol	HAE3, HAEX, HAF
Species	Human
Gene Type	protein-coding
Description	coagulation factor XII (Hageman factor)
Other Description	Hageman factor|beta-factor XIIa part 1|beta-factor XIIa part 2|coagulation factor XII|coagulation factor XIIa heavy chain|coagulation factor XIIa light chain
Swissprots	P78339 P00748
Accessions	AAB51203 AAB51204 AAB51205 AAB51206 AAB51207 AAB59490 AAB59491 AAM97932 CAK18991 EAW85002 EAW85003 EAW85004 EAW85005 P00748 AB095845 BAC23095 BC012390 AAH12390 BC168381 AAI68381 BE139501 BT007350 AAP36014 M11723 AAA51986 M13147 AAA70224 M31315 AAA70225 XM_011534461 XP_011532763 XM_011534462 XP_011532764 NM_000505 NP_000496
Function	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. {ECO:0000269|PubMed:21304106}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-F12-cDNA-Clone - DC03394 from Abgent, a WuXi AppTec company Prices $405.00 Sizes 10 µg Species Human Accession BC012390

F12 - MBS1273651 from MyBioSource Prices $315.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC012390

Human F12 ORF Clone(NM_000505.3) - CDCL162793 from Creative Biomart Species Human Accession NM_000505.3

Human F12 ORF Clone(NM_000505.3) - CDCL162794 from Creative Biomart Species Human Accession NM_000505.3

Human Factor XII heavy chain Gene ORF cDNA clone in cloning vector - HG12281-G from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12281-ACR from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid - HG12281-UT from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, C-His tag - HG12281-CH from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12281-ACG from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12281-NF from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12281-NM from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, C-HA tag - HG12281-CY from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12281-CF from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12281-CM from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, N-HA tag - HG12281-NY from Sino Biological Species Human

Human Factor XII heavy chain Gene ORF cDNA clone expression plasmid, N-His tag - HG12281-NH from Sino Biological Species Human

Human F12 ORF Clone (BC012390) - CDCS405704 from Creative biogene Species Human Accession P00748

Human F12 ORF clone (BC012390) - CDCB160154 from Creative biogene Species Human

Human F12 Gene cDNA Clone - orb143099 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Search more