F12

Gene Symbol	F12
Entrez Gene	2161
Alt Symbol	HAE3, HAEX, HAF
Species	Human
Gene Type	protein-coding
Description	coagulation factor XII (Hageman factor)
Other Description	Hageman factor|beta-factor XIIa part 1|beta-factor XIIa part 2|coagulation factor XII|coagulation factor XIIa heavy chain|coagulation factor XIIa light chain
Swissprots	P78339 P00748
Accessions	AAB51203 AAB51204 AAB51205 AAB51206 AAB51207 AAB59490 AAB59491 AAM97932 CAK18991 EAW85002 EAW85003 EAW85004 EAW85005 P00748 AB095845 BAC23095 BC012390 AAH12390 BC168381 AAI68381 BE139501 BT007350 AAP36014 M11723 AAA51986 M13147 AAA70224 M31315 AAA70225 XM_011534461 XP_011532763 XM_011534462 XP_011532764 NM_000505 NP_000496
Function	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. {ECO:0000269|PubMed:21304106}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

F12-Over-expression-Lysate - LY12757a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

F12 293T Cell Transient Overexpression Lysate(Denatured) - H00002161-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

Human Factor XII (Factor 12) Deficient Plasma (EDTA) - D101204 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Plasma (EDTA) - D101205 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Plasma (EDTA) - D101206 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Plasma (Heparin) - D101207 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Plasma (Heparin) - D101208 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Plasma (Heparin) - D101209 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Plasma (Sodium Citrate) - D101201 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Plasma (Sodium Citrate) - D101202 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Plasma (Sodium Citrate) - D101203 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Factor XII (Factor 12) Deficient Serum - D101210 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Serum

Human Factor XII (Factor 12) Deficient Serum - D101211 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Serum

Human Factor XII (Factor 12) Deficient Serum - D101212 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Serum

Factor XII Overexpression Lysate (Denatured) - H00002161-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human F12 Knockdown Stable Cell Line - CSC-DC005167 from Creative biogene Category Cell Line Species Human

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