Gene Symbol | ABCA3 |
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Entrez Gene | 21 |
Alt Symbol | ABC-C, ABC3, EST111653, LBM180, SMDP3 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family A (ABC1), member 3 |
Other Description | ABC transporter 3|ABC-C transporter|ATP-binding cassette sub-family A member 3|ATP-binding cassette transporter 3 |
Swissprots | Q99758 Q92473 B2RU09 Q6P5P9 Q54A95 |
Accessions | AAY57325 EAW85515 Q99758 AB070929 BAB86781 AB210044 BAE06126 AK310864 BC020724 AAH20724 BC035752 BC062779 AAH62779 BC140895 AAI40896 BC146866 AAI46867 BC151840 AAI51841 BP397501 DA109409 U78735 AAC50967 X97187 CAA65825 NM_001089 NP_001080 |
Function | Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma. |
Top Pathways | ABC transporters |
Human ATP-binding cassette sub-family A member 3 protein fragment - ab125999 from Abcam
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ABCA3 fusion protein - ag9840 from Proteintech Group
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ABCA3 fusion protein - ag9810 from Proteintech Group
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Recombinant Human ABCA3, GST-tagged - ABCA3-9205H from Creative Biomart
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Recombinant Human ABCA3 - ABCA3-546H from Creative Biomart
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Recombinant ATP Binding Cassette Transporter A3 (ABCA3) - RPD619Hu01 from Uscn Life Science Inc.
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Recombinant Human FGF-21 (Carrier-free) - 21-7055 from Tonbo Biosciences
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Recombinant ATP Binding Cassette Transporter A3 (ABCA3) - RPD619Hu01 from Cloud-clone
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ABCA3 Recombinant Protein Antigen - NBP1-89310PEP from Novus Biologicals
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ABCA3 Peptide, Human - M34GP00033H from Creative Peptides
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ATP-binding cassette sub-family A member 3 (1686-1694) - ta-065 from Creative Peptides
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ABCA3 Recombinant Protein (OPCD01005) - OPCD01005 from Aviva Systems Biology
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ABCA3 fusion protein - Ag24749 from Proteintech Group
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ABCA3 fusion protein - Ag24759 from Proteintech Group
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Recombinant Human ABCA3 protein, His & T7-tagged - ABCA3-8114H from Creative Biomart
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