Gene Symbol | ABCA3 |
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Entrez Gene | 21 |
Alt Symbol | ABC-C, ABC3, EST111653, LBM180, SMDP3 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family A (ABC1), member 3 |
Other Description | ABC transporter 3|ABC-C transporter|ATP-binding cassette sub-family A member 3|ATP-binding cassette transporter 3 |
Swissprots | Q99758 Q92473 B2RU09 Q6P5P9 Q54A95 |
Accessions | AAY57325 EAW85515 Q99758 AB070929 BAB86781 AB210044 BAE06126 AK310864 BC020724 AAH20724 BC035752 BC062779 AAH62779 BC140895 AAI40896 BC146866 AAI46867 BC151840 AAI51841 BP397501 DA109409 U78735 AAC50967 X97187 CAA65825 NM_001089 NP_001080 |
Function | Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma. |
Top Pathways | ABC transporters |
ABCA3 (C-18) - sc-48442 from Santa Cruz Biotechnology
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ABCA3 (N-20) - sc-48444 from Santa Cruz Biotechnology
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ABCA3 (H-120) - sc-134560 from Santa Cruz Biotechnology
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ABCA3 (C-16) - sc-48441 from Santa Cruz Biotechnology
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Anti-ABCA3 antibody - ab186192 from Abcam
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Anti-ABCA3 antibody - N-terminal - ab187755 from Abcam
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Anti-ATP-binding cassette sub-family A member 3 antibody - ab99856 from Abcam
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Anti-ABCA3 Antibody - LS-C346373 from LifeSpan Bioscience
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Anti-ABCA3 Antibody (aa271-288) - LS-C313351 from LifeSpan Bioscience
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ABCA3 Antibody - 38280002 from Novus Biologicals
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ABCA3 Antibody - NBP1-89310 from Novus Biologicals
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Anti-ABCA3 antibody produced in rabbit - HPA007884 from Sigma-Aldrich
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ABCA3 antibody - orb77619 from Biorbyt
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ABCA3 Polyclonal Antibody - A6862 from ABclonal
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ABCA3 Antibody - abx038096 from Abbexa
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ABCA3 Antibody - abx005231 from Abbexa
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Anti-ABCA3, Polyclonal Antibody - 25-A6862 from ARP American Research Products
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Anti-ABCA3 antibody - STJ28942 from St John's Laboratory Ltd
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P180 Lamellar Body Protein, Polyclonal Antibody - MBS176772 from MyBioSource
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ABCA3 Antibody - E305064 from Enogene
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ABCA3 , Polyclonal Antibody - MBS9125772 from MyBioSource
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ABCA3, Polyclonal Antibody - MBS855986 from MyBioSource
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Anti-ABCA3 polyclonal antibody - DPABT-H7500 from Creative Diagnostics
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Monoclonal Antibody to ATP Binding Cassette Transporter A3 (ABCA3) - MAD619Hu21 from Uscn Life Science Inc.
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Polyclonal Antibody to ATP Binding Cassette Transporter A3 (ABCA3) - PAD619Hu01 from Uscn Life Science Inc.
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