RBBP4

Gene Symbol RBBP4
Entrez Gene 5928
Alt Symbol NURF55, RBAP48, lin-53
Species Human
Gene Type protein-coding
Description retinoblastoma binding protein 4
Other Description CAF-1 subunit C|CAF-I 48 kDa subunit|CAF-I p48|MSI1 protein homolog|RBBP-4|chromatin assembly factor 1 subunit C|chromatin assembly factor I p48 subunit|chromatin assembly factor/CAF-1 p48 subunit|histone-binding protein RBBP4|nucleosome-remodeling factor subunit RBAP48|retinoblastoma-binding protein 4|retinoblastoma-binding protein p48
Swissprots Q53H02 D3DPQ3 P31149 Q09028 Q96BV9 B4DRH0 B2R6G9
Accessions CAH61602 EAX07513 EAX07514 EAX07515 Q09028 AK056356 AK056550 AK222779 BAD96499 AK299251 BAG61282 AK299410 BAG61392 AK312571 BAG35466 BC003092 AAH03092 BC015123 AAH15123 BC053904 AAH53904 BC075836 AAH75836 BT007309 AAP35973 DC315298 DQ892499 ABM83425 DQ895712 ABM86638 X71810 CAA50685 X74262 CAA52321 NM_001135255 NP_001128727 NM_001135256 NP_001128728 NM_005610 NP_005601
Function Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. {ECO:0000269|PubMed:10866654}.
Subcellular Location Nucleus.

Human RbAp48 full length protein - ab132949 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132949 stained with Coomassie Blue

Human RbAp48 full length protein - ab130037 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE showing ab130037 (3 µg).

Human RbAp48 full length protein - ab196431 from Abcam

Category Protein
Source Baculovirus infected sf9 cells
Species Human
SDS-PAGE analysis of 5 μg ab196431 on 10% SDS-PAGE gel stained with Coomassie.

Human RbAp48 peptide - ab38404 from Abcam

Category Peptide

Human RbAp48 peptide - ab61624 from Abcam

Category Peptide

Human RbAp48 protein fragment - ab93983 from Abcam

Category Protein
Source E. coli
Species Human
The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

RbAp48 peptide - ab5014 from Abcam

Category Peptide

RBBP4 / RBAP48 Antibody Blocking Peptide - LS-E20598 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RBBP4/RbAp48 Recombinant Protein - H00005928-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human RBBP4/RbAp48 Protein - NBP1-98868 from Novus Biologicals

Category Protein
Prices $269.00, $729.00
Sizes 100 µg, 500 µg
Source E.coli
Species Human

Human RBBP4 His tag protein - orb83973 from Biorbyt

Category Protein
Prices $323.00, $612.00
Sizes 20 μg, 50 μg
Source Insect
Species Human
SDS-PAGE analysis of Human RBBP4 His tag protein

Human RBBP4 protein - orb169168 from Biorbyt

Category Protein
Prices $230.00, $442.00
Sizes 5 μg, 20 μg
Source E.coli
Species Human

RBBP4 Blocking Peptide - 33R-3865 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

RBBP4 protein (His tag) - 80R-2399 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

RBBP4 / RBAP48 (1-425, His-tag) - AR50480PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
RBBP4 / RBAP48

RBBP4 / RBAP48 (1-425, His-tag) - AR50480PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
RBBP4 / RBAP48

RBBP4 / RBAP48 - H00005928-P01-02 from Acris Antibodies

Category Protein
Prices $300.00
Sizes 2 µg
Source in vitro transl.
Species Human

RBBP4 / RBAP48 control peptide - SP5325CP from Acris Antibodies

Category Peptide
Prices $205.00
Sizes 50 µg

RBBP4, 1-425aa Human, His tag, E.coli - 01-P1656 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

RBBP4 fusion protein - Ag6110 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

RBBP4 fusion protein - Ag6196 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

RbAp48, Active Human Recombinant Protein - GWB-74261D from Genway Biotech

Category Protein
Prices $600.00
Sizes 50 µg
Species Human
RbAp48, Active Human Recombinant Protein

RBBP4, 1-425aa Human, His tag, E.coli - GWB-P0382E from Genway Biotech

Category Protein
Prices $300.00, $900.00
Sizes 100 μg, 500 μg
Source E.coli
Species Human

Recombinant Human RBBP4, His-tagged - RBBP4-28145TH from Creative Biomart

Category Protein
Source E. coli

Recombinant Human Retinoblastoma Binding Protein 4, His-tagged - RBBP4-6964H from Creative Biomart

Category Protein
Source E. coli
Species Human
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