Gene Symbol | RBBP4 |
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Entrez Gene | 5928 |
Alt Symbol | NURF55, RBAP48, lin-53 |
Species | Human |
Gene Type | protein-coding |
Description | retinoblastoma binding protein 4 |
Other Description | CAF-1 subunit C|CAF-I 48 kDa subunit|CAF-I p48|MSI1 protein homolog|RBBP-4|chromatin assembly factor 1 subunit C|chromatin assembly factor I p48 subunit|chromatin assembly factor/CAF-1 p48 subunit|histone-binding protein RBBP4|nucleosome-remodeling factor subunit RBAP48|retinoblastoma-binding protein 4|retinoblastoma-binding protein p48 |
Swissprots | Q53H02 D3DPQ3 P31149 Q09028 Q96BV9 B4DRH0 B2R6G9 |
Accessions | CAH61602 EAX07513 EAX07514 EAX07515 Q09028 AK056356 AK056550 AK222779 BAD96499 AK299251 BAG61282 AK299410 BAG61392 AK312571 BAG35466 BC003092 AAH03092 BC015123 AAH15123 BC053904 AAH53904 BC075836 AAH75836 BT007309 AAP35973 DC315298 DQ892499 ABM83425 DQ895712 ABM86638 X71810 CAA50685 X74262 CAA52321 NM_001135255 NP_001128727 NM_001135256 NP_001128728 NM_005610 NP_005601 |
Function | Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. {ECO:0000269|PubMed:10866654}. |
Subcellular Location | Nucleus. |
Human RbAp48 full length protein - ab132949 from Abcam
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Human RbAp48 full length protein - ab130037 from Abcam
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Human RbAp48 full length protein - ab196431 from Abcam
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Human RbAp48 peptide - ab38404 from Abcam
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Human RbAp48 peptide - ab61624 from Abcam
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Human RbAp48 protein fragment - ab93983 from Abcam
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RbAp48 peptide - ab5014 from Abcam
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RBBP4 / RBAP48 Antibody Blocking Peptide - LS-E20598 from LifeSpan Bioscience
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RBBP4/RbAp48 Recombinant Protein - H00005928-P01 from Novus Biologicals
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Recombinant Human RBBP4/RbAp48 Protein - NBP1-98868 from Novus Biologicals
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Human RBBP4 His tag protein - orb83973 from Biorbyt
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Human RBBP4 protein - orb169168 from Biorbyt
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RBBP4 Blocking Peptide - 33R-3865 from Fitzgerald
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RBBP4 protein (His tag) - 80R-2399 from Fitzgerald
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RBBP4 / RBAP48 (1-425, His-tag) - AR50480PU-N from Acris Antibodies
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RBBP4 / RBAP48 (1-425, His-tag) - AR50480PU-S from Acris Antibodies
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RBBP4 / RBAP48 - H00005928-P01-02 from Acris Antibodies
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RBBP4 / RBAP48 control peptide - SP5325CP from Acris Antibodies
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RBBP4, 1-425aa Human, His tag, E.coli - 01-P1656 from ARP American Research Products
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RBBP4 fusion protein - Ag6110 from Proteintech Group
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RBBP4 fusion protein - Ag6196 from Proteintech Group
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RbAp48, Active Human Recombinant Protein - GWB-74261D from Genway Biotech
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RBBP4, 1-425aa Human, His tag, E.coli - GWB-P0382E from Genway Biotech
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Recombinant Human RBBP4, His-tagged - RBBP4-28145TH from Creative Biomart
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Recombinant Human Retinoblastoma Binding Protein 4, His-tagged - RBBP4-6964H from Creative Biomart
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