CERS5

Gene Symbol CERS5
Entrez Gene 91012
Alt Symbol LASS5, Trh4
Species Human
Gene Type protein-coding
Description ceramide synthase 5
Other Description LAG1 homolog, ceramide synthase 5|LAG1 longevity assurance homolog 5
Swissprots B4DV54 Q8N5B7
Accessions CAH05418 EAW58131 EAW58132 EAW58133 Q8N5B7 AK026014 AK027087 AK055740 AK058033 AK294521 BAG57732 AK298924 BAG61029 AK300937 BAG62566 AK308930 BC014637 BC032565 AAH32565 BC033558 AAH33558 DA230084 HY016808 U15426 XM_005269220 XP_005269277 XM_006719687 XP_006719750 XM_011538975 XP_011537277 XR_429120 NM_001281731 NP_001268660 NM_147190 NP_671723 NR_104035
Function Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

LASS5 CRISPR/Cas9 KO Plasmid (h) - sc-404525 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LASS5 HDR Plasmid (h) - sc-404525-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LASS5 Double Nickase Plasmid (h) - sc-404525-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LASS5 Double Nickase Plasmid (h2) - sc-404525-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LASS5 CRISPR Activation Plasmid (h) - sc-404525-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LASS5 CRISPR Activation Plasmid (h2) - sc-404525-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LASS5 Lentiviral Activation Particles (h) - sc-404525-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LASS5 Lentiviral Activation Particles (h2) - sc-404525-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LASS5 siRNA (h) - sc-62551 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LASS5 shRNA Plasmid (h) - sc-62551-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LASS5 shRNA (h) Lentiviral Particles - sc-62551-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU001981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11564 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11564 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06110 from Sigma-Aldrich

Category miRNA

CERS5 siRNA (Human) - CRJ4005 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Lass5 RNAi - H00091012-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CERS5 - MBS8224585 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Cers5 (NM_147190.2) - SHH262129 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LASS5(NM_147190.2) - SHH142985 from Creative biogene

Category siRNA
Species Reactivities Human

CERS5 shRNA Plasmid (Human) - CHJ4005 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CERS5 miRNA 3'UTR clone - MiUTR1H-05583 from Creative biogene

Species Reactivities Human
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