Gene Symbol | CERS5 |
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Entrez Gene | 91012 |
Alt Symbol | LASS5, Trh4 |
Species | Human |
Gene Type | protein-coding |
Description | ceramide synthase 5 |
Other Description | LAG1 homolog, ceramide synthase 5|LAG1 longevity assurance homolog 5 |
Swissprots | B4DV54 Q8N5B7 |
Accessions | CAH05418 EAW58131 EAW58132 EAW58133 Q8N5B7 AK026014 AK027087 AK055740 AK058033 AK294521 BAG57732 AK298924 BAG61029 AK300937 BAG62566 AK308930 BC014637 BC032565 AAH32565 BC033558 AAH33558 DA230084 HY016808 U15426 XM_005269220 XP_005269277 XM_006719687 XP_006719750 XM_011538975 XP_011537277 XR_429120 NM_001281731 NP_001268660 NM_147190 NP_671723 NR_104035 |
Function | Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Sphingolipid signaling pathway, Sphingolipid metabolism |
Human Lass5 protein fragment - ab164839 from Abcam
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LASS5 Antibody Blocking Peptide - LS-E12920 from LifeSpan Bioscience
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LASS5 Antibody Blocking Peptide - LS-E13564 from LifeSpan Bioscience
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LASS5 Antibody Blocking Peptide - LS-E26828 from LifeSpan Bioscience
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LASS5 Antibody Blocking Peptide - LS-E30618 from LifeSpan Bioscience
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LASS5 Antibody Blocking Peptide - LS-E30534 from LifeSpan Bioscience
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LASS5 Antibody Blocking Peptide - LS-E30533 from LifeSpan Bioscience
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LASS5 Blocking Peptide - 33R-10943 from Fitzgerald
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LASS5 Peptide - AC21-1660-P from Abcore
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LASS5 - H00091012-Q01-10 from Acris Antibodies
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LASS5 - H00091012-Q01-25 from Acris Antibodies
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LASS5 Control Peptide - AP30490CP-N from Acris Antibodies
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LASS5 Control Peptide - AP30491CP-N from Acris Antibodies
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LASS5 Control Peptide - AP30492CP-N from Acris Antibodies
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LASS5 Peptide - 42-752P from ProSci
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LASS5 Peptide - 4695P from ProSci
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LASS5 Peptide - 4939P from ProSci
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LASS5 Peptide - 4697P from ProSci
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Recombinant Human CERS5 - CERS5-1400H from Creative Biomart
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LASS5 Blocking Peptide - 3830BP-50 from Biovision
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LASS5, Peptide - MBS843861 from MyBioSource
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LASS5+6/CerS5+6, Peptide - MBS425959 from MyBioSource
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LASS5 fusion protein - Ag26160 from Proteintech Group
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Ceramide synthase 5 (CERS5), Recombinant Protein - MBS7011392 from MyBioSource
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LASS5 Immunizing peptide - orb15444 from Biorbyt
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