CERS5

Gene Symbol CERS5
Entrez Gene 91012
Alt Symbol LASS5, Trh4
Species Human
Gene Type protein-coding
Description ceramide synthase 5
Other Description LAG1 homolog, ceramide synthase 5|LAG1 longevity assurance homolog 5
Swissprots B4DV54 Q8N5B7
Accessions CAH05418 EAW58131 EAW58132 EAW58133 Q8N5B7 AK026014 AK027087 AK055740 AK058033 AK294521 BAG57732 AK298924 BAG61029 AK300937 BAG62566 AK308930 BC014637 BC032565 AAH32565 BC033558 AAH33558 DA230084 HY016808 U15426 XM_005269220 XP_005269277 XM_006719687 XP_006719750 XM_011538975 XP_011537277 XR_429120 NM_001281731 NP_001268660 NM_147190 NP_671723 NR_104035
Function Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

LASS5 (N-14) - sc-65124 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LASS5 (N-14): sc-65124. Western blot analysis of LASS5 expression in HeLa (A) and Jurkat (B) whole cell lysates and HeLa (C) and Jurkat (D) nuclear extracts.

LASS5 (H-45) - sc-135038 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Lass5 antibody - ab73289 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Lass5 antibody (ab73289) at 1 µg/mlLane 2 : Anti-Lass5 antibody (ab73289) at 2 µg/mlLane 1 : rat brain tissue lysateLane 2 : rat brain tissue lysateLysates/proteins at 15 µg per lane.

Anti-Lass5 antibody - ab115314 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Lass5 antibody (ab115314) at 1 µg/mlLane 1 : SK-N-SH cell lysateLane 2 : SK-N-SH cell lysate with blocking peptide

Anti-Lass5 antibody - ab87131 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Lass5 antibody (ab87131) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal kidney lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Lass5 antibody - ab63927 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Lass5 antibody (ab63927) at 0.5 µg/ml + Jurkat cell lysate

Anti-LASS5 Antibody - LS-C146973 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LASS5 Antibody (aa341-354) - LS-C112757 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-LASS5 Antibody (N-Terminus) - LS-C82889 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of LASS5 in SK-N-SH lysate with LASS5 antibody at (A) 1 and (B) 2 ug/ml

Anti-LASS5 Antibody (aa72-121) - LS-C110220 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LASS5 antibody LS-C110220 Western blot of Fetal Pancreas lysate.

Anti-LASS5 Antibody (aa71-120) - LS-C101604 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LASS5 antibody LS-C101604 Western blot of Fetal Kidney lysate.

Anti-LASS5 Antibody (N-Terminus) - LS-C83889 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of LASS5 in Human Brain cells with LASS5 antibody at 20 ug/ml.

Anti-LASS5 Antibody (C-Terminus) IHC-plus™ - LS-B3152 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LASS5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3152 concentration 5 ug/ml.

Lass5 Antibody - NBP1-76964 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Lass5 Antibody [NBP1-76964] - SK-N-SH lysate with LASS5 antibody at (A) 1 and (B) 2 ug/ml.

Lass5 Antibody - NBP1-77329 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Lass5 Antibody [NBP1-77329] - Rat brain tissue lysate with LASS5 antibody at (A) 1 and (B) 2 ug/ml.

Lass5 Antibody - NBP1-77328 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Lass5 Antibody [NBP1-77328] - SK-N-SH lysate with LASS5 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.

Lass5 Antibody - NBP1-00140 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-LASS5 antibody produced in rabbit - SAB3500440 from Sigma-Aldrich

Prices $348.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-LASS5: <B>Cat. No. SAB3500440</B>: Immunofluorescence of LASS5 in human brain tissue with LASS5 antibody at 20 μg/mL.

Anti-CERS5 antibody produced in rabbit - HPA026589 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LASS5: <B>Cat. No. HPA026589</B>: Immunohistochemical staining of human colon shows nucleolar positivity in glandular cells.

Anti-CERS5 antibody produced in rabbit - SAB4301211 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LASS5 antibody produced in rabbit - SAB2101322 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LASS5: <B>Cat. No.SAB2101322</B>: LASS5 in Fetal Pancreas tissue lysate with LASS5 antibody at 1.0 μg/mL.

LASS5 antibody - N-terminal region (ARP36161_P050) - ARP36161_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LASS5 antibody - N-terminal region (ARP37810_P050) - ARP37810_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LASS56--CerS56-Antibody-internal-region - AF2819a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

LASS5 antibody - orb75025 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of rat brain tissue lysate at (A) 1 and (B) 2 ug/mL using LASS5 antibody
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