| Gene Symbol |
CERS5
|
| Entrez Gene |
91012
|
| Alt Symbol |
LASS5, Trh4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ceramide synthase 5
|
| Other Description |
LAG1 homolog, ceramide synthase 5|LAG1 longevity assurance homolog 5
|
| Swissprots |
B4DV54 Q8N5B7
|
| Accessions |
CAH05418 EAW58131 EAW58132 EAW58133 Q8N5B7 AK026014 AK027087 AK055740 AK058033 AK294521 BAG57732 AK298924 BAG61029 AK300937 BAG62566 AK308930 BC014637 BC032565 AAH32565 BC033558 AAH33558 DA230084 HY016808 U15426 XM_005269220 XP_005269277 XM_006719687 XP_006719750 XM_011538975 XP_011537277 XR_429120 NM_001281731 NP_001268660 NM_147190 NP_671723 NR_104035
|
| Function |
Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Sphingolipid signaling pathway, Sphingolipid metabolism
|