SLC1A1

Gene Symbol	SLC1A1
Entrez Gene	6505
Alt Symbol	DCBXA, EAAC1, EAAT3, SCZD18
Species	Human
Gene Type	protein-coding
Description	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
Other Description	excitatory amino acid carrier 1|excitatory amino acid transporter 3|neuronal and epithelial glutamate transporter|sodium-dependent glutamate/aspartate transporter 3|solute carrier family 1 member 1
Swissprots	Q9UEW2 Q8N199 O75587 Q5VZ24 P43005
Accessions	AAC27511 EAW58786 P43005 AB008536 BAB83767 AF037982 AAC25029 AK313013 BAG35848 BC033040 AAH33040 BQ008494 BQ029108 CB984615 CK903716 DA643262 DQ892425 ABM83351 DQ895639 ABM86565 U03506 AAA50430 U06469 AAA53215 U08989 AAA68628 XM_011518007 XP_011516309 XM_011518008 XP_011516310 XM_011518009 XP_011516311 XM_011518010 XP_011516312 NM_004170 NP_004161
Function	Transports L-glutamate, L- and D-aspartate and L-cystein (PubMed:21123949). Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5 (By similarity). {ECO:0000250|UniProtKB:P51906, ECO:0000250|UniProtKB:P51907, ECO:0000269|PubMed:21123949}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:21123949}; Multi-pass membrane protein. Apical cell membrane {ECO:0000269|PubMed:21123949}; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Tissue Specificity	Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers). {ECO:0000269|PubMed:7521911, ECO:0000269|PubMed:7859077, ECO:0000269|PubMed:7914198}.
Top Pathways	Protein digestion and absorption, Glutamatergic synapse

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SLC1A1 / EAAT3 ELISA Kit (Sandwich ELISA) - LS-F8983 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.117 ng/ml Range 0.313-20 ng/ml

Human EAAT3 ELISA Kit - abx151370 from Abbexa Category ELISA Kit Sensitivity 0.117 ng/ml Range 0.313 ng/ml - 20 ng/ml

Excitatory Amino Acid Transporter 3 (EAAT3), Human, ELISA Kit - SEE342Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.117ng/mL Range 0.312-20ng/mL

Excitatory Amino Acid Transporter 3, ELISA Kit - MBS099085 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Excitatory Amino Acid Transporter 3, ELISA Kit - MBS071975 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Excitatory Amino Acid Transporter 3, ELISA Kit - MBS066857 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Excitatory Amino Acid Transporter 3, ELISA Kit - MBS070969 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Excitatory Amino Acid Transporter 3, ELISA Kit - MBS067173 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Excitatory Amino Acid Transporter 3, ELISA Kit - MBS079252 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Excitatory Amino Acid Transporter 3, ELISA Kit - MBS095398 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Excitatory Amino Acid Transporter 3 (EAAT3), ELISA Kit - MBS2023644 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human EAAT3 is typically less than 0.117ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL

solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag) , member 1, ELISA Kit - MBS9330467 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Excitatory Amino Acid Transporter 3 (EAAT3) - SEE342Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.117ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Excitatory Amino Acid Transporter 3 (EAAT3) - SEE342Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.117ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Excitatory Amino Acid Transporter 3 (EAAT3) ELISA Kit - EKU03994 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.117 ng/mL Range 0.312-20 ng/mL

Excitatory Amino Acid Transporter 3 (EAAT3), Human, ELISA Kit - DL-EAAT3-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human EAAT3(Excitatory Amino Acid Transporter 3) ELISA Kit - E-EL-H5591 from Elabscience Category ELISA Kit Sensitivity 0.47 ng/mL Range 0.78—50 ng/mL

Human EAAT3 ELISA Kit - abx573020 from Abbexa Category ELISA Kit Sensitivity 0.117 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human EAAT3 ELISA Kit - E013813 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human EAAT3 is typically less than 0.117ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by add

Human SLC1A1 ELISA Kit - E035826 from Biobool Category ELISA Kit

SLC1A1 ELISA Kit (Human) (OKCD00934) - OKCD00934 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.117 ng/mL Range 0.312-20 ng/mL

Human EAAT3(Excitatory Amino Acid Transporter 3) ELISA Kit - E-EL-H5591 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.47 ng/mL Range 0.78~50 ng/mL

Human Excitatory amino acid transporter 3 (SLC1A1) ELISA Kit - AE19094HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.117 ng/mL Range 0.312-20 ng/mL

Excitatory Amino Acid Transporter 3, ELISA Kit - MBS2533406 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

Excitatory Amino Acid Transporter 3 (EAAT3), ELISA Kit - MBS452267 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.117ng/mL Range 0.312-20ng/mL

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