SPTLC1

Gene Symbol SPTLC1
Entrez Gene 10558
Alt Symbol HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI
Species Human
Gene Type protein-coding
Description serine palmitoyltransferase, long chain base subunit 1
Other Description LCB 1|SPT 1|long chain base biosynthesis protein 1|serine C-palmitoyltransferase|serine palmitoyltransferase 1|serine-palmitoyl-CoA transferase 1
Swissprots A8K681 O15269 Q96IX6 Q5VWB4
Accessions AAK29328 CCQ43355 EAW62804 EAW62805 EAW62806 O15269 AB209757 BAD92994 AF147304 AK098344 AK291546 BAF84235 AK299153 BAG61202 AK309775 BC007085 AAH07085 BC068537 AAH68537 DA305642 EC564300 Y08685 CAA69941 XM_011518138 XP_011516440 XM_011518139 XP_011516441 NM_001281303 NP_001268232 NM_006415 NP_006406 NM_178324 NP_847894
Function Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1- SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. {ECO:0000269|PubMed:19416851}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Not detected in small intestine. {ECO:0000269|PubMed:17023427}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

Mouse SPTLC1 / HSN1 ELISA Kit (Sandwich ELISA) - LS-F7312 from LifeSpan Bioscience

Category ELISA Kit
Prices $740.00
Sizes 1 plate
Sensitivity 0.055 ng/ml
Range 0.156-10 ng/ml

serine palmitoyltransferase, long chain base subunit 1, ELISA Kit - MBS9331983 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine Palmitoyltransferase, Long Chain Base Subunit 1, ELISA Kit - MBS102673 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine Palmitoyltransferase, Long Chain Base Subunit 1, ELISA Kit - MBS055324 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine Palmitoyltransferase, Long Chain Base Subunit 1, ELISA Kit - MBS077882 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine Palmitoyltransferase, Long Chain Base Subunit 1, ELISA Kit - MBS084356 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine Palmitoyltransferase, Long Chain Base Subunit 1, ELISA Kit - MBS089738 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine Palmitoyltransferase, Long Chain Base Subunit 1, ELISA Kit - MBS077750 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine Palmitoyltransferase, Long Chain Base Subunit 1, ELISA Kit - MBS086517 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1), ELISA Kit - MBS2022714 from MyBioSource

Category ELISA Kit
Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.055ng/mL.
Range 0.156-10ng/mL

ELISA Kit for Serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) - SEH138Mu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human SPTLC1 ELISA Kit - E034712 from Biobool

Category ELISA Kit

Serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1), ELISA Kit - MBS9375480 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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