PROK1

Gene Symbol	PROK1
Entrez Gene	84432
Alt Symbol	EGVEGF, PK1, PRK1
Species	Human
Gene Type	protein-coding
Description	prokineticin 1
Other Description	EG-VEGF|black mamba toxin-related protein|endocrine-gland-derived vascular endothelial growth factor|mambakine|prokineticin-1
Swissprots	Q5VWD4 P58294 Q8TC69
Accessions	CAI59103 CAN87427 EAW56449 EAW56450 P58294 AF333024 AAK49918 AY029225 AAK33111 AY358683 AAQ89046 BC025399 AAH25399 BM544315 DQ891570 ABM82496 DQ894763 ABM85689 NM_032414 NP_115790
Function	Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. {ECO:0000269|PubMed:11259612, ECO:0000269|PubMed:11528470, ECO:0000269|PubMed:15292351, ECO:0000269|PubMed:17289879, ECO:0000269|PubMed:18339712}.
Subcellular Location	Secreted.
Tissue Specificity	Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. {ECO:0000269|PubMed:11528470, ECO:0000269|PubMed:15292351, ECO:0000269|PubMed:18339712}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EG-VEGF (PK1) Human ELISA Kit - ab119591 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 7 pg/ml Range 15.6 pg/ml - 1000 pg/ml

Human PROK1 / EG-VEGF ELISA Kit (Sandwich ELISA) - LS-F2586 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 7 pg/ml Range 13.71-3333 pg/ml

Human PROK1 / EG-VEGF ELISA Kit (Sandwich ELISA) - LS-F3980 from LifeSpan Bioscience Category ELISA Kit Prices $480.00 Sizes 1 plate Sensitivity 6.3 pg/ml Range 13.71-3333 pg/ml

Mouse PROK1 / EG-VEGF ELISA Kit (Sandwich ELISA) - LS-F5450 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 13.71-3333 pg/ml

Rat PROK1 / EG-VEGF ELISA Kit (Sandwich ELISA) - LS-F5449 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 6.5 pg/ml Range 13.71-3333 pg/ml

Bovine PROK1 / EG-VEGF ELISA Kit (Sandwich ELISA) - LS-F6251 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 6.3 pg/ml Range 13.71-3333 pg/ml

Human PROK1 / EG-VEGF ELISA Kit (Sandwich ELISA) - LS-F71 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 13.71 pg/ml Range 13.71-3333 pg/ml

Human PROK1 / EG-VEGF ELISA Kit (Sandwich ELISA) - LS-F559 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 13.71-3333 pg/ml

Human PROK1 / EG-VEGF ELISA Kit (Sandwich ELISA) - LS-F12423 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 7.8 Range 13.71-3333 pg/ml

Human EG-VEGF / PK1  ELISA Kit - RAB0410 from Sigma-Aldrich Category ELISA Kit Prices $666.00 Sizes 1 kt

Human EG-VEGF/PK1 DuoSet ELISA - DY1209 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Human EGVEGF ELISA Kit - 55R-1712 from Fitzgerald Category ELISA Kit Prices $440.00 Sizes 1 kit

EG-VEGF ELISA Kit (Human) : 96 Wells (OKAG00013) - OKAG00013 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 16 pg/mL Range 16-1,000 pg/mL

Human EG-VEGF ELISA Kit - abx056142 from Abbexa Category ELISA Kit

Human EG-VEGF ELISA Kit - abx151388 from Abbexa Category ELISA Kit Sensitivity 7.2 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Human EG-VEGF ELISA Kit - abx054869 from Abbexa Category ELISA Kit

Human EG-VEGF ELISA kit - abx050056 from Abbexa Category ELISA Kit Sensitivity < 7pg/ml Range 15.6 pg/ml-1000 pg/ml

EG-VEGF, Human, ELISA Kit - BEK1046 from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity < 7pg/ml Range 15.6 pg/ml-1000 pg/ml

EG-VEGF, Human, ELISA Kit - PB-0575 from ARP American Research Products Category ELISA Kit Prices $449.00 Sizes 96 t Sensitivity < 7 pg/ml Range 15.6pg/ml-1000pg/ml

Endocrine Gland Derived Vascular Endothelial Growth Factor, EG-VEGF, Human, ELISA Kit - E-EL-H0061 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

Prokineticin 1 (PROK1/EG-VEGF), Human, ELISA Kit - CSB-E04532h from ARP American Research Products Category ELISA Kit Prices $450.00, $595.00, $596.00, $599.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Prokineticin-1, PROK1, Human, ELISA Kit - E0024h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 7.8-500 pg/mL

Endocrine Gland Vascular Endothelial Growth Factor, EG-VEGF, Rat, ELISA Kit - E-EL-R0361 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Endocrine Gland Derived Vascular Endothelial Growth Factor, EG-VEGF/PK1, Rabbit, ELISA Kit - E-EL-RB2074 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Endocrine Gland Derived Vascular Endothelial Growth Factor, EG-VEGF, Chicken, ELISA Kit - E-EL-Ch2187 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

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