PROK1

Gene Symbol PROK1
Entrez Gene 84432
Alt Symbol EGVEGF, PK1, PRK1
Species Human
Gene Type protein-coding
Description prokineticin 1
Other Description EG-VEGF|black mamba toxin-related protein|endocrine-gland-derived vascular endothelial growth factor|mambakine|prokineticin-1
Swissprots Q5VWD4 P58294 Q8TC69
Accessions CAI59103 CAN87427 EAW56449 EAW56450 P58294 AF333024 AAK49918 AY029225 AAK33111 AY358683 AAQ89046 BC025399 AAH25399 BM544315 DQ891570 ABM82496 DQ894763 ABM85689 NM_032414 NP_115790
Function Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. {ECO:0000269|PubMed:11259612, ECO:0000269|PubMed:11528470, ECO:0000269|PubMed:15292351, ECO:0000269|PubMed:17289879, ECO:0000269|PubMed:18339712}.
Subcellular Location Secreted.
Tissue Specificity Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. {ECO:0000269|PubMed:11528470, ECO:0000269|PubMed:15292351, ECO:0000269|PubMed:18339712}.

EG-VEGF (E-12) - sc-390741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EG-VEGF (E-12): sc-390741. Western blot analysis of EG-VEGF expression in non-transfected (A) and human EG-VEGF transfected (B) PROK1 whole cell lysates.

EG-VEGF (H-40) - sc-48835 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

EG-VEGF (P-15) - sc-30345 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EG-VEGF (T-16) - sc-21022 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EG-VEGF (A-12) - sc-30343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Prokineticin 1 antibody - ab42802 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
ab42802 at 0.33 µg/ml staining Prokinectin 1 in tissue of chorionic villi at 9 weeks of gestation. Staining can be observed in Cytotrophoblast (Cyt), Hobfauer cells (Ho), Extravillous trophoblast (Evt) and Syncytiotrophoblast (St). Negative control with preimmune serum shows no staining. Counterstaining performed with haematoxylin.

Anti-Prokineticin 1 antibody - ab169152 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Prokineticin 1 antibody (ab169152) at 1 µg/mlLane 1 : Prokineticin 1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-Prokineticin 1 antibody - ab17535 from Abcam

Prices $370.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-Prokineticin 1 antibody - ab110625 from Abcam

Prices $0.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-Prokineticin 1 antibody (Biotin) - ab84014 from Abcam

Prices $370.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-Prokineticin 1 antibody [EPR9699] - ab150375 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9699
All lanes : Anti-Prokineticin 1 antibody [EPR9699] (ab150375) at 1/1000 dilutionLane 1 : Raw 264.7 cell lysate.Lane 2 : NIH/3T3 cell lysate.Lane 3 : ECV-304 cell lysate.Lysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Prokineticin 1 antibody [MM0043-2L13] - ab72807 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0043-2L13
ab72807 at 1/100 dilution, staining Prokineticin 1 in human placenta tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

Anti-PROK1 / EG-VEGF Antibody - LS-C126160 from LifeSpan Bioscience

Prices $635.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PROK1 / EG-VEGF Antibody (Biotin) - LS-C131582 from LifeSpan Bioscience

Prices $650.00
Sizes 50 µg
Host Sheep
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody (N-Terminus) - LS-C144642 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody (aa81-105, Biotin) - LS-C184090 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody (aa81-105, CF) - LS-C184091 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody (aa81-105, Cy3) - LS-C184092 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody (aa81-105, Cy5) - LS-C184093 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody (aa81-105, Rhodamine) - LS-C184094 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody (aa81-105) - LS-C191229 from LifeSpan Bioscience

Prices $740.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody - LS-C342161 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PROK1 / EG-VEGF Antibody - LS-C146916 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of PROK1 / EG-VEGF antibody LS-C146916.

Anti-PROK1 / EG-VEGF Antibody (aa1-105) - LS-C314342 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PROK1 / EG-VEGF.

Anti-PROK1 / EG-VEGF Antibody - LS-C104481 from LifeSpan Bioscience

Prices $285.00, $325.00
Sizes 50 µg, 100 µg
Host Goat
Clonality Polyclonal
Sandwich ELISA of PROK1 / EG-VEGF antibody LS-C104481
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