TP53BP1

Gene Symbol	TP53BP1
Entrez Gene	7158
Alt Symbol	53BP1, p202, p53BP1
Species	Human
Gene Type	protein-coding
Description	tumor protein p53 binding protein 1
Other Description	p53-binding protein 1|tumor protein 53-binding protein, 1|tumor protein p53-binding protein, 1|tumor suppressor p53-binding protein 1
Swissprots	Q2M1Z7 Q7Z3U4 Q12888 Q5FWZ3 Q4LE46 F8VY86
Accessions	AAW69392 EAW92604 EAW92605 Q12888 AB210025 BAE06107 AF078776 AAC62018 AK123418 BAG53901 AK125173 AK292915 BAF85604 AK295764 BAH12183 AK307405 BC017846 AAH17846 BC063119 BC112161 AAI12162 BP228994 BX537418 CAD97660 U09477 AAA21596 XM_005254635 XP_005254692 XM_011521984 XP_011520286 XM_011521985 XP_011520287 XM_011521986 XP_011520288 XR_931898 XR_931899 NM_001141979 NP_001135451 NM_001141980 NP_001135452 NM_005657 NP_005648
Function	Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation. {ECO:0000269|PubMed:12364621, ECO:0000269|PubMed:17190600, ECO:0000269|PubMed:21144835}.
Subcellular Location	Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. H4K20me2 is required for efficient localization to double strand breaks and removal of proteins that have a high affinity for H4K20me2 such as L3MBTL1 and KDM4A is needed.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Goat anti-53BP1 Antibody, Affinity Purified - PLA0303 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Rabbit anti-53BP1 Antibody, Affinity Purified - PLA0077 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Rabbit anti-Phospho 53BP1 (S25) Antibody, Affinity Purified - PLA0126 from Sigma-Aldrich Prices $345.00 Sizes 100 µl

Mouse/Human/Rat Phospho-TP53BP1 / 53BP1 (Ser6) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1284 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.313-20 ng/ml

Mouse/Human/Rat TP53BP1 / 53BP1 ELISA Kit (Cell-Based ELISA) - LS-F1771 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.313-20 ng/ml

Human TP53BP1 / 53BP1 ELISA Kit (Sandwich ELISA) - LS-F9012 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.138 ng/ml Range 0.313-20 ng/ml

Tumor Protein p53 Binding Protein 1 (TP53BP1), Human, ELISA Kit - SEH009Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.138ng/mL Range 0.312-20ng/mL

Tumor suppressor p53-binding protein 1 (TP53BP1), Human, ELISA Kit - CSB-EL024080HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 1.56 pg/ml Range 6.25 pg/ml-400 pg/ml

53BP1 Colorimetric Cell-Based ELISA Kit - CB5009 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

53BP1 (Phospho-Ser6) Colorimetric Cell-Based ELISA Kit - CBP1286 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

tumor protein p53 binding protein 1, ELISA Kit - MBS924744 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.56 pg/ml Range 6.25 pg/ml-400 pg/ml

Tumor Protein p53 Binding Protein 1 (TP53BP1), ELISA Kit - MBS2023431 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human TP53BP1 is typically less than 0.138ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL

ELISA Kit for Tumor Protein p53 Binding Protein 1 (TP53BP1) - SEH009Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.138ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Tumor suppressor p53-binding protein 1(TP53BP1) ELISA kit - CSB-EL024080HU from Cusabio Category ELISA Kit Sensitivity 1.56 pg/ml Range 6.25 pg/ml-400 pg/ml

ELISA Kit for Tumor Protein p53 Binding Protein 1 (TP53BP1) - SEH009Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.138ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human TP53BP1 ELISA Kit - abx153357 from Abbexa Category ELISA Kit Sensitivity 0.138 ng/ml Range 0.313 ng/ml - 20 ng/ml

Tumor Protein p53 Binding Protein 1 (TP53BP1), Human, ELISA Kit - DL-TP53BP1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

53BP1 ELISA Kit - DEIA-XYA142 from Creative Diagnostics Category ELISA Kit

53BP1 (Phospho-Ser6) ELISA Kit - DEIA-XYA143 from Creative Diagnostics Category ELISA Kit

Human TP53BP1 ELISA Kit - abx573030 from Abbexa Category ELISA Kit Sensitivity 0.138 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human TP53BP1 ELISA Kit - E040027 from Biobool Category ELISA Kit Sensitivity 1.56 pg/ml

TP53BP1 ELISA Kit (Human) (OKCD01016) - OKCD01016 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.138 ng/mL Range 0.312-20 ng/mL

anti-TP53BP1 antibody - ARG56882 from Arigo Biolaboratories Category ELISA Kit

Human Tumor suppressor p53-binding protein 1 (TP53BP1) ELISA Kit - AE13748HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.138 ng/mL Range 0.312-20 ng/mL

TP53BP1 (Tumor Protein p53 Binding Protein 1), ELISA Kit - MBS7606555 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/ml Range 31.25-2000pg/ml

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