BCR

Gene Symbol BCR
Entrez Gene 613
Alt Symbol ALL, BCR1, CML, D22S11, D22S662, PHL
Species Human
Gene Type protein-coding
Description breakpoint cluster region
Other Description BCR/FGFR1 chimera protein|FGFR1/BCR chimera protein|breakpoint cluster region protein|renal carcinoma antigen NY-REN-26
Swissprots Q6NZI3 P11274 Q12842 Q4LE80
Accessions AAA35594 AAA35596 AAB60388 AAB60389 AAB60390 CAA37010 CAA37011 EAW59564 EAW59565 EAW59566 EAW59567 EAW59568 EAW59569 EAW59570 P11274 AB209991 BAE06073 AB742170 BAM36291 AB742171 BAM36292 AF192533 AAF61858 AF321981 AF487522 AAL99544 AK122842 AK124310 AK128501 AK303241 BAG64327 AY533677 AAS57923 AY536244 AAS46906 AY536245 AAS46907 AY536246 AAS46908 AY536247 AAS46909 AY536248 AAS46910 AY536249 AAS46911 AY536250 AAS46912 BC031568 BC041705 BC053641 BC063619 BC066122 BC071742 BC083493 AAH83493 BC169208 BQ422888 EU216058 ABX82700 EU216059 ABX82701 EU216061 ABX82703 EU216062 ABX82704 EU216063 ABX82705 EU216064 ABX82706 EU216067 ABX82709 EU216069 ABX82711 EU216070 ABX82712 HQ622706 ADU04570 M17542 AAA35595 M64437 AAN76489 X02596 CAA26441 X06418 CAA29726 X14675 CAA32805 X14676 CAA32806 X14677 Y00661 CAA68676 NM_004327 NP_004318 NM_021574 NP_067585
Function GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity. {ECO:0000269|PubMed:1657398, ECO:0000269|PubMed:1903516}.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250|UniProtKB:Q6PAJ1}.
Top Pathways Chronic myeloid leukemia

Phospho-Bcr (Tyr177) Antibody - 3901 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from K562 cells, untreated or calf intestinal phosphatase (CIP)-treated, using Phospho-Bcr (Tyr177) Antibody (upper) or Bcr Antibody #3902 (lower).

Bcr Antibody - 3902 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from K562, MCF-7 and HepG2 cells, using Bcr Antibody.

Bcr (B-12) - sc-28375 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bcr (B-12): sc-28375. Western blot analysis of Bcr expression in K-562 (A) and BJAB (B) whole cell lysates.

Bcr (C-20) - sc-886 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Bcr (C-20): sc-886. Western blot analysis of Bcr expression in K-562 (A) and HeLa (B) whole cell lysates.

Bcr (7C6) - sc-103 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Bcr (G6) - sc-104 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bcr (G6): sc-104. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing cytoplasmic staining of glandular cells.

Bcr (H-300) - sc-20707 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Bcr (H-300): sc-20707. Immunofluorescence staining of methanol-fixed A-431 cells showing nuclear and cytoplasmic localization.

Bcr (H-5) - sc-48422 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bcr (H-5): sc-48422. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

Bcr (4C12) - sc-53178 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Bcr (N-20) - sc-885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Bcr (N-20): sc-885. Western blot analysis of Bcr/Abl p210 (A) and Bcr p160 (B-D) expression in K-562 (A), HeLa (B), BJAB (C) and A-431 (D) whole cell lysates.

p-Bcr (Tyr 177) - sc-101645 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-Bcr (Tyr 177): sc-101645. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human tonsil tumor tissue extract showing cytolasmic staining.

Anti-Bcr (phospho Y177) antibody - ab194762 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bcr (phospho Y177) antibody (ab194762) at 1/500 dilutionLane 1 : Extract from K562 cells, untreatedLane 2 : Extract from K562 cells treated with hydrogen peroxide

Anti-Bcr (phospho Y177) antibody - ab192180 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bcr (phospho Y177) antibody (ab192180) at 1/500 dilutionLane 1 : K562 whole cell lysate with antigen-specific peptideLane 2 : K562 whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-Bcr (phospho Y177) antibody - ab51040 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bcr (phospho Y177) antibody (ab51040) at 1/500 dilutionLane 1 : K562 cell extract, treated with the immunising peptide.Lane 2 : K562 cell extract, untreated.

Anti-Bcr (phospho Y177) antibody [EPR576(2)Y] - ab68216 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR576(2)Y
All lanes : Anti-Bcr (phospho Y177) antibody [EPR576(2)Y] (ab68216) at 1/1000 dilutionLane 1 : 3T3 cell lysate, membrane un-treatedLane 2 : 3T3 cell lysate, membrane treated with pervanadateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Bcr (phospho Y360) antibody - ab195734 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bcr (phospho Y360) antibody (ab195734) at 1/500 dilutionLane 1 : COS7 whole cell lysate with antigen-specific peptideLane 2 : COS7 whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-Bcr (phospho Y360) antibody - ab194529 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bcr (phospho Y360) antibody (ab194529) at 1/500 dilutionLane 1 : COS7 extractLane 2 : COS7 extract with antigen-specific peptide

Anti-Bcr (phospho Y360) antibody - ab59404 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded human brain tissue using ab59404 at 1/50 dilution, in the presence (right) and absence (left) of phosphopeptide.

Anti-Bcr antibody - ab86173 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of human K562 cells labelling Bcr with ab86173 at 1/1000 (1µg/ml). An Alexa Fluor® 488-conjugated goat anti-rabbit IgG (1/1000) was used as the secondary antibody.

Anti-Bcr antibody - ab32523 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Bcr antibody - ab51087 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bcr antibody (ab51087) at 1/500 dilutionLane 1 : K562 cell extractLane 2 : K562 cell extract + blocking peptide

Anti-Bcr antibody - ab87269 from Abcam

Prices $380.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab87269 at 1/250 dilution staining Bcr in human K562 cells by Immunofluorescence, Formalin-fixed, Paraffin-embedded tissue. Detection: Red fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte PlusTM 555 used at a dilution of 1/100.

Anti-Bcr antibody - ab59352 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab59352, at a 1/50-1/100 dilution, staining human Bcr in brain with (+) or without (-) immunising peptide, using Immunohistochemistry, Paraffin embedded tissue

Anti-Bcr antibody - ab167344 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Bcr antibody (ab167344) at 1 µg/mlLane 1 : Bcr transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.

Anti-Bcr antibody [EP535Y] - ab40779 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP535Y
ab40779, staining human lymphoma by immunohistochemistry, paraffin embedded tissue.
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