Gene Symbol | PIGK |
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Entrez Gene | 10026 |
Alt Symbol | GPI8 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class K |
Other Description | GPI transamidase subunit|GPI-anchor transamidase|GPI8 homolog|PIG-K|phosphatidylinositol glycan, class K|phosphatidylinositol-glycan biosynthesis class K protein |
Swissprots | B4E2M3 B2R7K3 Q5TG77 O14822 Q92643 |
Accessions | EAX06380 EAX06381 EAX06382 EAX06383 Q92643 AF022913 AAB81597 AK055071 AK304340 BAG65185 AK313015 BAG35850 BC020737 AAH20737 BC026186 BX648473 DA263434 HQ447704 ADQ32189 Y07596 CAA68871 NM_005482 NP_005473 |
Function | Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:11483512}; Single-pass type I membrane protein {ECO:0000269|PubMed:11483512}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
Human PIGK protein fragment - ab160770 from Abcam
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PIGK Antibody Blocking Peptide - LS-E14836 from LifeSpan Bioscience
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PIGK Antibody Blocking Peptide - LS-E14837 from LifeSpan Bioscience
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PIGK Antibody Blocking Peptide - LS-E6966 from LifeSpan Bioscience
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PIGK Antibody Blocking Peptide - LS-E6967 from LifeSpan Bioscience
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GPI8 Partial Recombinant Protein - H00010026-Q01 from Novus Biologicals
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GPI8 Peptide - P1112 from Novus Biologicals
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GPI8 Peptide - P1111 from Novus Biologicals
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GPI8-Antibody-C-term-Blocking-Peptide - BP2462b from Abgent, a WuXi AppTec company
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GPI8-Antibody-N-term-Blocking-Peptide - BP2462a from Abgent, a WuXi AppTec company
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PIGK Blocking Peptide - 33R-8936 from Fitzgerald
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PIGK Blocking Peptide - 33R-5803 from Fitzgerald
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PIGK - H00010026-Q01-10 from Acris Antibodies
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PIGK - H00010026-Q01-25 from Acris Antibodies
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PIGK fusion protein - ag7766 from Proteintech Group
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PIGK fusion protein - ag3497 from Proteintech Group
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Recombinant Human PIGK, His-tagged - PIGK-1706H from Creative Biomart
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Recombinant Human GPI-anchor transamidase(PIGK) - CSB-YP842143HU CSB-EP842143HU CSB-BP842143HU CSB-MP842143HU from Cusabio
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GPI8 Recombinant Protein Antigen - NBP2-33812PEP from Novus Biologicals
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GPI8 Recombinant Protein Antigen - NBP2-33782PEP from Novus Biologicals
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PIGK Peptide, Human - M34GP11760H from Creative Peptides
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