Gene Symbol | PIGK |
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Entrez Gene | 10026 |
Alt Symbol | GPI8 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class K |
Other Description | GPI transamidase subunit|GPI-anchor transamidase|GPI8 homolog|PIG-K|phosphatidylinositol glycan, class K|phosphatidylinositol-glycan biosynthesis class K protein |
Swissprots | B4E2M3 B2R7K3 Q5TG77 O14822 Q92643 |
Accessions | EAX06380 EAX06381 EAX06382 EAX06383 Q92643 AF022913 AAB81597 AK055071 AK304340 BAG65185 AK313015 BAG35850 BC020737 AAH20737 BC026186 BX648473 DA263434 HQ447704 ADQ32189 Y07596 CAA68871 NM_005482 NP_005473 |
Function | Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:11483512}; Single-pass type I membrane protein {ECO:0000269|PubMed:11483512}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-K (G-6) - sc-398611 from Santa Cruz Biotechnology
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PIG-K (V-20) - sc-54973 from Santa Cruz Biotechnology
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PIG-K (C-25) - sc-130233 from Santa Cruz Biotechnology
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Anti-PIGK antibody - ab38443 from Abcam
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Anti-PIGK antibody - ab38445 from Abcam
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Anti-PIGK antibody [EPR17843] - ab201693 from Abcam
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Anti-PIGK Antibody (C-Terminus, AP) - LS-C277644 from LifeSpan Bioscience
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Anti-PIGK Antibody (C-Terminus, APC) - LS-C277645 from LifeSpan Bioscience
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Anti-PIGK Antibody (C-Terminus, Biotin) - LS-C277646 from LifeSpan Bioscience
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Anti-PIGK Antibody (C-Terminus, FITC) - LS-C277647 from LifeSpan Bioscience
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Anti-PIGK Antibody (C-Terminus, Azide-free, HRP) - LS-C277648 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus, AP) - LS-C277649 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus, APC) - LS-C277650 from LifeSpan Bioscience
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Anti-PIGK Antibody (C-Terminus, PE) - LS-C277651 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus, Biotin) - LS-C277652 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus, FITC) - LS-C277653 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus, Azide-free, HRP) - LS-C277654 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus, PE) - LS-C277655 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus) - LS-C327447 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus) - LS-C327449 from LifeSpan Bioscience
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Anti-PIGK Antibody (N-Terminus) - LS-C101857 from LifeSpan Bioscience
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Anti-PIGK Antibody (aa67-116) - LS-C80353 from LifeSpan Bioscience
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Anti-PIGK Antibody (aa266-297) - LS-C98457 from LifeSpan Bioscience
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Anti-PIGK Antibody (aa37-68) - LS-C98456 from LifeSpan Bioscience
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GPI8 Antibody - NBP2-33812 from Novus Biologicals
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