FAIM3

Gene Symbol	FAIM3
Entrez Gene	9214
Alt Symbol	FCMR, TOSO
Species	Human
Gene Type	protein-coding
Description	Fas apoptotic inhibitory molecule 3
Other Description	Fc mu receptor|IgM Fc receptor|fas apoptotic inhibitory molecule 3|immunoglobulin mu Fc receptor|regulator of Fas-induced apoptosis Toso
Swissprots	O60667 B7Z6Z0 D9MWM3 A8K7J2
Accessions	CBX53827 EAW93517 O60667 AA769146 AF057557 AAC18830 AI524407 AK292007 BAF84696 AK297053 BAH12483 AK301187 BAH13426 AK316336 BAH14707 BC006401 AAH06401 BP225124 BP305798 BP338035 BT006797 AAP35443 CB158779 DA971987 DB122623 DC393681 DQ890699 ABM81625 GQ160900 ACX94154 GQ160901 ACX94155 HM480394 ADK11426 XM_005273351 XP_005273408 XM_005273352 XP_005273409 XR_921999 NM_001142472 NM_001142473 NP_001135945 NM_001193338 NP_001180267 NM_005449 NP_005440
Function	May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. {ECO:0000269|PubMed:9586636}.
Subcellular Location	Isoform 1: Membrane; Single-pass membrane protein.
Tissue Specificity	Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland. Expressed in lymphoid cell lines such as Jurkat, CEM-T4, MOLT-4, HB11;19 and Reh. No expression detected in nonhematopoietic cell lines including Hep-G2, HEK293 and HeLa. Detected at high levels in chronic lymphocytic leukemia cells. {ECO:0000269|PubMed:21908424, ECO:0000269|PubMed:9586636}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FAIM3 full length protein - ab160385 from Abcam Category Protein Source Wheat germ Species Human

Human FAIM3 protein fragment - ab160386 from Abcam Category Protein Source Wheat germ Species Human

FCMR / FAIM3 Antibody Blocking Peptide - LS-E29934 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human FAIM3 Protein - H00009214-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human FAIM3 Protein - H00009214-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

FAIM3 Blocking Peptide - NBP1-76458PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Human FAIM3 protein - orb138840 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

FAIM3 / TOSO - H00009214-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

FAIM3 / TOSO - H00009214-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

FAIM3 / TOSO - H00009214-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

FAIM3 / TOSO - H00009214-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FAIM3 / TOSO - H00009214-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FAIM3 / TOSO Control Peptide - AP30932CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Toso Peptide - 2273P from ProSci Category Peptide Species Human

Recombinant Human FAIM3, Fc-tagged - FAIM3-277H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Fas Apoptotic Inhibitory Molecule 3 (FAIM3) - RPK403Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Human FAIM3 Protein (Fc Tag) - 13556-H02H-50 from Sino Biological Category Protein Source Human Cells Species Human

Recombinant Fas Apoptotic Inhibitory Molecule 3 (FAIM3) - RPK403Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Fas apoptotic inhibitory molecule 3(FAIM3) - CSB-YP007972HU CSB-EP007972HU CSB-BP007972HU CSB-MP007972HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FAIM3 Recombinant Protein Antigen - NBP1-86924PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FAIM3 Peptide, Human - M34GP05207H from Creative Peptides Category Peptide Source Synthetic. Species Human

Fas apoptotic inhibitory molecule 3, Recombinant Protein - MBS7042706 from MyBioSource Category Protein Prices $1,180.00, $2,165.00, $3,375.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Fas apoptotic inhibitory molecule 3 (FAIM3), Recombinant Protein - MBS1040717 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Fas:Fc, Recombinant Protein - MBS636741 from MyBioSource Category Protein Prices $535.00 Sizes 50 µg Source Human, HEK 293 cells Species Human, Mouse

Human FAIM3 Protein (Fc Tag) - 13556-H02H from ABclonal Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

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