FAIM3

Gene Symbol FAIM3
Entrez Gene 9214
Alt Symbol FCMR, TOSO
Species Human
Gene Type protein-coding
Description Fas apoptotic inhibitory molecule 3
Other Description Fc mu receptor|IgM Fc receptor|fas apoptotic inhibitory molecule 3|immunoglobulin mu Fc receptor|regulator of Fas-induced apoptosis Toso
Swissprots O60667 B7Z6Z0 D9MWM3 A8K7J2
Accessions CBX53827 EAW93517 O60667 AA769146 AF057557 AAC18830 AI524407 AK292007 BAF84696 AK297053 BAH12483 AK301187 BAH13426 AK316336 BAH14707 BC006401 AAH06401 BP225124 BP305798 BP338035 BT006797 AAP35443 CB158779 DA971987 DB122623 DC393681 DQ890699 ABM81625 GQ160900 ACX94154 GQ160901 ACX94155 HM480394 ADK11426 XM_005273351 XP_005273408 XM_005273352 XP_005273409 XR_921999 NM_001142472 NM_001142473 NP_001135945 NM_001193338 NP_001180267 NM_005449 NP_005440
Function May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. {ECO:0000269|PubMed:9586636}.
Subcellular Location Isoform 1: Membrane; Single-pass membrane protein.
Tissue Specificity Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland. Expressed in lymphoid cell lines such as Jurkat, CEM-T4, MOLT-4, HB11;19 and Reh. No expression detected in nonhematopoietic cell lines including Hep-G2, HEK293 and HeLa. Detected at high levels in chronic lymphocytic leukemia cells. {ECO:0000269|PubMed:21908424, ECO:0000269|PubMed:9586636}.

Toso (N-20) - sc-8263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Toso (RR-16) - sc-101253 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Toso (RR-16): sc-101253. Western blot analysis of Toso expression in K-562 whole cell lysate.

Anti-FAIM3 antibody - ab56487 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FAIM3 antibody - ab197950 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-FAIM3 antibody (ab197950) at 1/200 dilution + Human lymphoma tissue lysate at 40 µg

Anti-FAIM3 antibody - ab168968 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-FAIM3 antibody (ab168968) at 1 µg/mlLane 1 : FAIM3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-FAIM3 antibody - ab115211 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115211, at 5 ug/ml, staining FAIM3 in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-FAIM3 antibody - ab47882 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FAIM3 antibody (ab47882) at 1 µg/mlLane 1 : Human lung tissue lysate with blocking peptide presentLane 2 : Human lung tissue lysate with blocking peptide absentLysates/proteins at 15 µg per lane.

Anti-FAIM3 antibody [EPR3811] - ab134116 from Abcam

Host Rabbit
Clonality Monoclonal
Clone EPR3811
All lanes : Anti-FAIM3 antibody [EPR3811] (ab134116) at 1/1000 dilutionLane 1 : Human spleen lysateLane 2 : Human fetal lung lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP conjugated antibody at 1/2000 dilution

Anti-FCMR / FAIM3 Antibody (C-Terminus) IHC-plus™ - LS-B1353 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FAIM3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1353 concentration 5 ug/ml.

Anti-FCMR / FAIM3 Antibody (aa124-223) - LS-C307965 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FCMR / FAIM3 Antibody - LS-C307961 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-FCMR / FAIM3 Antibody - LS-C311126 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FCMR / FAIM3 Antibody (clone 1E6) - LS-C338495 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6
IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-FAIM3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-FCMR / FAIM3 Antibody - LS-C335653 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using FAIM3 antibody.

Anti-TOSO / FAIM3 Antibody (Internal, clone EPR3811) - LS-C137999 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone [EPR3811]
Western blot analysis on (A) human spleen and (B) fetal lung lysates using anti-TOSO / FAIM3 antibody.

FAIM3 Antibody (1E4) - H00009214-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E4
Western Blot: FAIM3 Antibody (1E4) [H00009214-M01] - FAIM3 monoclonal antibody (M01), clone 1E4 Analysis of FAIM3 expression in K-562.

FAIM3 Antibody - NBP1-86924 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FAIM3 Antibody [NBP1-86924] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

FAIM3 Antibody - H00009214-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: FAIM3 Antibody [H00009214-B01] - FAIM3 MaxPab polyclonal antibody (B01), Lot # 07288WULz. Western Blot analysis of FAIM3 expression in human spleen.

FAIM3 Antibody - H00009214-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

FAIM3 Antibody - H00009214-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: FAIM3 Antibody [H00009214-B02P] - Analysis of FAIM3 expression in transfected 293T cell line by FAIM3 polyclonal antibody. Lane 1: FAIM3 transfected lysate(42.9 KDa). Lane 2: Non-transfected lysate.

FAIM3 Antibody - H00009214-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: FAIM3 Antibody [H00009214-B02] - FAIM3 expression in transfected 293T cell line by FAIM3 MaxPab polyclonal antibody (B02). Lane 1: FAIM3 transfected lysate (43.10 KDa). Lane 2: Non-transfected lysate.

FAIM3 Antibody - NBP1-02719 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: FAIM3 Antibody [NBP1-02719] - Staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

FAIM3 Antibody - H00009214-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FAIM3 Antibody [H00009214-D01P] - Analysis of FAIM3 expression in mouse testis.

FAIM3 Antibody - NBP1-76458 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FAIM3 Antibody [NBP1-76458] - Analysis of TOSO in K562 cell lysate with TOSO antibody at (A) 1 and (B) 2 ug/mL.

FAIM3 Polyclonal Antibody - bs-7527R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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