RAD9A

Gene Symbol	RAD9A
Entrez Gene	5883
Alt Symbol	RAD9
Species	Human
Gene Type	protein-coding
Description	RAD9 homolog A (S. pombe)
Other Description	DNA repair exonuclease rad9 homolog A|cell cycle checkpoint control protein RAD9A|hRAD9
Swissprots	B2RCZ8 Q96C41 Q6FI29 Q99638
Accessions	AAU89725 BAH69085 BAH69086 BAH69087 EAW74604 EAW74605 EAW74606 Q99638 AA708970 AK310213 AK315348 BAG37745 BC014848 AAH14848 CB164642 CN402466 CR536508 CAG38746 U53174 AAB39928 XM_006718652 XP_006718715 XM_011545205 XP_011543507 XR_428922 NM_001243224 NP_001230153 NM_004584 NP_004575
Function	Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity. Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12628935}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Rad9 protein fragment - ab159300 from Abcam Category Protein Source Wheat germ Species Human

RAD9A / RAD9 Antibody Blocking Peptide - LS-E1040 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD9A / RAD9 Antibody Blocking Peptide - LS-E2257 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD9A / RAD9 Antibody Blocking Peptide - LS-E10524 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD9A / RAD9 Antibody Blocking Peptide - LS-E7307 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD9A / RAD9 Antibody Blocking Peptide - LS-E7308 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD9A / RAD9 Antibody Blocking Peptide - LS-E7309 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD9A / RAD9 Antibody Blocking Peptide - LS-E7305 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD9A / RAD9 Antibody Blocking Peptide - LS-E7306 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD9A / RAD9 Antibody Blocking Peptide - LS-E26228 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Rad9 Protein - H00005883-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Rad9 Peptide - P1390 from Novus Biologicals Category Peptide Species Human

Rad9 Peptide - P1398 from Novus Biologicals Category Peptide Species Human

Rad9 Peptide - P1391 from Novus Biologicals Category Peptide Species Human

Rad9 Peptide - P1392 from Novus Biologicals Category Peptide Species Human

Rad9 Peptide - P1397 from Novus Biologicals Category Peptide Species Human

Rad9-Antibody-S387-Blocking-peptide - BP11518a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAD9-Antibody-BH3-Domain-Specific-Blocking-peptide - BP1318a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-RAD9Y28-Antibody-Blocking-peptide - BP3231a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-RAD9S387-Antibody-Blocking-peptide - BP3230a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-RAD9S328-Antibody-Blocking-peptide - BP3225a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-RAD9S277-Antibody-Blocking-peptide - BP3224a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-RAD9S272-Antibody-Blocking-peptide - BP3223a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

RAD9A blocking peptide - GTX89156-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog

Goat anti RAD9A antibody Immunizing peptide - orb16142 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

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